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【medical-news】U.S. study looks at second opinions in breast cancer

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U.S. study looks at second opinions in breast cancer
11/30/2006
By: Reuters Health

WASHINGTON (Reuters), Nov 30 - Breast cancer patients were urged to change their treatment plans more than half the time when they received a second opinion from a team of specialists, U.S. researchers reported on Wednesday.
Overall, 52% of patients whose original diagnosis and treatment recommendations were taken to a multidisciplinary team were advised to make one or more changes in their treatment, the researchers at the University of Michigan Comprehensive Cancer Center found.

The changes were a result of breast imaging specialists reading a mammogram differently or breast pathologists interpreting biopsy results differently, the researchers reported in this week's issue of the journal Cancer.

The team, called a multidisciplinary tumor board, included surgeons, radiation oncologists, medical oncologists, radiologists, and pathologists.

"A multidisciplinary tumor board that involves the collaborative effort of multiple medical specialties allows expert opinion and recommendations based on the most recent research findings," said Dr. Michael Sabel, a surgeon who worked on the study.

"Meanwhile, the patients come to only one setting, with no need to visit multiple specialists individually."

His team looked at the records of 149 breast cancer patients referred to the Cancer Center's multidisciplinary breast tumor board for a second opinion.

They found the original doctors often did not consider new surgery techniques, such as delivering chemotherapy before surgery to help save more of the breast, or sentinel lymph node biopsy, a new technique that helps find whether cancer has spread beyond the breast.

And radiologists reinterpreted imaging results in 45% of patients, in some cases identifying previously undiagnosed second cancers.

More than a quarter of patients were advised to have another biopsy.

Specialized breast pathologists made new interpretations of how aggressive a tumor, or what type of tumor it was, in 29% of patients, the researchers found.

More than 200,000 U.S. women will be diagnosed with breast cancer this year, according to the American Cancer Society, and 40,000 will die of it. Globally, 500,000 women die every year from breast cancer.

Last Updated: 2006-11-30 10:05:37 -0400 (Reuters Health)

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2006-12-02 17:11 浏览 : 512 回复 : 3

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本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。

2006-12-03 15:35

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U.S. study looks at second opinions in breast cancer
11/30/2006
By: Reuters Health
美国研究关注乳癌第二意见
WASHINGTON (Reuters), Nov 30 - Breast cancer patients were urged to change their treatment plans more than half the time when they received a second opinion from a team of specialists, U.S. researchers reported on Wednesday.
Overall, 52% of patients whose original diagnosis and treatment recommendations were taken to a multidisciplinary team were advised to make one or more changes in their treatment, the researchers at the University of Michigan Comprehensive Cancer Center found.
华盛顿（路透社）11月30日-美国研究人员星期三报告，乳癌患者接受专家组第二意见时，超过一半的他们被动员改变治疗计划。
密执安大学综合肿瘤中心的研究者报告，总共有52%的患者被多学科小组劝告在治疗上对原来的治疗计划作一处或一处以上的修改。
The changes were a result of breast imaging specialists reading a mammogram differently or breast pathologists interpreting biopsy results differently, the researchers reported in this week's issue of the journal Cancer.
在这个星期出版的癌症杂志上，研究者认为，这种改变是由于乳房影像专家阅读乳房X线照片不同或者乳房病理学专家解释活检结果不同。
The team, called a multidisciplinary tumor board, included surgeons, radiation oncologists, medical oncologists, radiologists, and pathologists.
该小组，称作多学科肿瘤组，包括外科医生、放射肿瘤医生、肿瘤内科医生、放射科医生和病理学专家。
"A multidisciplinary tumor board that involves the collaborative effort of multiple medical specialties allows expert opinion and recommendations based on the most recent research findings," said Dr. Michael Sabel, a surgeon who worked on the study.
该研究的外科医生Michael Sabel,说：“多学科肿瘤小组，，对多个学科治疗协作，根据最新的研究结果提出专家意见和主张。”
"Meanwhile, the patients come to only one setting, with no need to visit multiple specialists individually."
“同时，患者只要到一个诊室。而不需一个一个地看专家。”
His team looked at the records of 149 breast cancer patients referred to the Cancer Center's multidisciplinary breast tumor board for a second opinion.
他的研究小组关注149例为第二意见到癌症中心多学科乳房肿瘤小组就诊的记录。
They found the original doctors often did not consider new surgery techniques, such as delivering chemotherapy before surgery to help save more of the breast, or sentinel lymph node biopsy, a new technique that helps find whether cancer has spread beyond the breast.
他们发现原来的医生没有考虑新的手术技术，如手术前化疗以保护更多的乳房，或前哨淋巴结活检新技术以发现是否有乳房外的癌转移。
And radiologists reinterpreted imaging results in 45% of patients, in some cases identifying previously undiagnosed second cancers.
放射科专家对45%的患者重新解释了影像学结果，有些患者，还发现先前没有诊断出的继发性癌症。
More than a quarter of patients were advised to have another biopsy.
超过1/4的患者被劝说再行活检。
Specialized breast pathologists made new interpretations of how aggressive a tumor, or what type of tumor it was, in 29% of patients, the researchers found.
研究者发现，乳癌病理学专家对29%患者的肿瘤浸润情况肿瘤类型作了新的评价。
More than 200,000 U.S. women will be diagnosed with breast cancer this year, according to the American Cancer Society, and 40,000 will die of it. Globally, 500,000 women die every year from breast cancer.
根据美国癌症学会资料，今年美国将有超过200,000名妇女被诊断患上乳癌，40，000死于乳癌。全球每年有500,000名妇女死于乳癌。

2006-12-03 20:36

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编译：
美国研究关注乳癌第二意见
路透社华盛顿11月30日消息，美国研究人员星期三报告，乳癌患者接受专家组第二意见时，超过一半的人被动员改变治疗计划。
密执安大学综合肿瘤中心的研究人员报告， 52%的患者被专家组劝说对原来的治疗计划作一处或一处以上的修改。在这个星期出版的癌症杂志上，研究者认为，这种改变是由于乳房影像专家阅读乳房X线片或者乳房病理学专家解释活检结果差异所致。
该专家小组，被称作多学科肿瘤小组，由外科医生、放疗科医生、肿瘤内科医生、放射科医生和病理学专家组成。多学科肿瘤小组的专家，根据最新的研究结果，对各个患者就治疗上的多个学科的协作，提出具体意见和主张。患者就诊也非常方便，不需一个一个地看专家。
研究小组查阅149例为第二意见到癌症中心多学科乳房肿瘤小组就诊的记录，发现原来的医生没有考虑新的手术技术，如手术前化疗以保护更多的乳房，或前哨淋巴结活检新技术以发现是否有乳房外的癌转移。45%患者影像学结果被重新解释，有些患者，还发现先前没有诊断出的继发性癌症。 29%患者的肿瘤浸润情况、肿瘤类型被重新评价，超过1/4的患者被劝说再行活检。
根据美国癌症学会资料，今年美国将有超过200,000名妇女被诊断患上乳癌，40，000死于乳癌。全球每年有500,000名妇女死于乳癌。

2006-12-03 21:05

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