发帖
每发1个新帖
可以获得0.5个丁当奖励
回帖

【medical-news】肥胖儿童的脂肪肝发生率有所升高

只看楼主
页码直达：
直达末页

楼主

丁香园中级站友

1楼

这个帖子发布于14年零33天前，其中的信息可能已发生改变或有所发展。

http://www.eurekalert.org/pub_releases/2007-03/iu-iof031507.php

Public release date: 15-Mar-2007

Incidence of Fatty Liver Disease rises as obesity in children increases
INDIANAPOLIS -- Indiana University School of Medicine researchers are taking a closer look at a disease whose incidence is rising as obesity in children increases. Non-Alcoholic Steatohepatitis, more popularly known as Fatty Liver Disease, occurs in approximately 15% of obese children. Fatty Liver Disease, in which fat accumulates in the liver, while not life threatening in children, can lead to cirrhosis (scarring) of the liver, sometimes requiring transplantation by adulthood.

"Until now the only treatment for Fatty Liver Disease has been to offer diet and exercise counseling, but this is often not effective. As part of a national multicenter research network, we are now looking at Vitamin E and at metformin, a drug used to treat Type II diabetes, as possible therapies" said Jean Molleston, M.D., clinical professor of pediatrics at IU School of Medicine and director of pediatric gastroenterology at Riley Hospital for Children. Dr. Molleston is the pediatric principal investigator for the IU School of Medicine site of TONIC, an eight-center Phase III study funded by the National Institute of Diabetes and Digestive and Kidney Disease, which is investigating treatment options for Fatty Liver Disease in 8 to 17 year olds and is the largest study of its type to date.

"We are seeing a growing number of young people with Fatty Liver Disease, and we need to tackle the disease before it becomes full blown in adulthood," said Dr. Molleston. "We routinely test children for conditions with much lower incidence such as scoliosis. Although we do not yet have formal guidelines for screening for Fatty Liver Disease, I personally think that all obese children should be screened for Fatty Liver Disease so we can intervene before it damages the liver."

A simple blood test to determine if liver enzyme levels are elevated alerts pediatricians that the child needs to be evaluated for Fatty Liver Disease.

Approximately a third of children and teens in the United States are overweight and 15% of children and teens are obese. Fatty Liver Disease may exist in 15% or more of obese children.

The American Liver Foundation estimates that 10-20% of Americans have Fatty Liver Disease.

邀请讨论

搜索

2007-03-16 22:24 浏览 : 646 回复 : 3

投票
收藏
打赏
引用
分享
- 微信扫一扫
- 新浪微博
- 丁香客
- 复制网址
举报
- 广告宣传推广
- 政治敏感、违法虚假信息
- 恶意灌水、重复发帖
- 违规侵权、站友争执
- 附件异常、链接失效
- 其他

• 2021内科主治专业实践能力

jie20088

丁香园准中级站友

2楼

本人认领此文。如在48小时内未能提交译文，其他战友可自由认领。

2007-03-16 22:28

投票
收藏
打赏
引用
分享
- 微信扫一扫
- 新浪微博
- 丁香客
- 复制网址
举报
- 广告宣传推广
- 政治敏感、违法虚假信息
- 恶意灌水、重复发帖
- 违规侵权、站友争执
- 附件异常、链接失效
- 其他

• 看乡镇医院如何留住人

jie20088

丁香园准中级站友

+1 积分
3楼

http://www.eurekalert.org/pub_releases/2007-03/iu-iof031507.php

Public release date: 15-Mar-2007
公开发行日期：2007年3月15日

Incidence of Fatty Liver Disease rises as obesity in children increases
肥胖儿童的脂肪肝发生率有所升高

INDIANAPOLIS -- Indiana University School of Medicine researchers are taking a closer look at a disease whose incidence is rising as obesity in children increases. Non-Alcoholic Steatohepatitis, more popularly known as Fatty Liver Disease, occurs in approximately 15% of obese children. Fatty Liver Disease, in which fat accumulates in the liver, while not life threatening in children, can lead to cirrhosis (scarring) of the liver, sometimes requiring transplantation by adulthood.
印第安纳波利斯——印第安纳大学医学院研究员对一种随着儿童肥胖度增加发生率升高的疾病进行了仔细的观察。非酒精性脂肪性肝，更普遍以脂肪肝著称，在极度肥胖的儿童中发生率大约15%。脂肪肝即脂肪在肝脏中积聚，儿时没有生命威胁，成年后可能导致肝硬化，有时还需要肝移植。

"Until now the only treatment for Fatty Liver Disease has been to offer diet and exercise counseling, but this is often not effective. As part of a national multicenter research network, we are now looking at Vitamin E and at metformin, a drug used to treat Type II diabetes, as possible therapies" said Jean Molleston, M.D., clinical professor of pediatrics at IU School of Medicine and director of pediatric gastroenterology at Riley Hospital for Children.
Dr. Molleston is the pediatric principal investigator for the IU School of Medicine site of TONIC, an eight-center Phase III study funded by the National Institute of Diabetes and Digestive and Kidney Disease, which is investigating treatment options for Fatty Liver Disease in 8 to 17 year olds and is the largest study of its type to date.
“到目前，对脂肪肝的唯一治疗是提供饮食和锻炼的建议，但是这经常是无效的。作为国际多渠道研究网络的一部分，我们当前正在关注维生素E和甲福明二甲双胍（一种治疗2型糖尿病的药物）作为可能的疗法。”身为IU（印第安纳大学）医学院儿科临床教授以及Riley医院儿科肠胃病学主管的Molleston, M.D如是说。Molleston博士是IU医学院开展的名为“ site of TONIC”项目的项目负责人。这个项目由国家糖尿病、消化系统与肾病研究院（the National Institute of Diabetes and Digestive and Kidney Disease）资助的8中心的三期研究，其目的是研究8-17岁的青少年脂肪肝的医疗方法，这是迄今为止同类研究中规模最大的一个。"We are seeing a growing number of young people with Fatty Liver Disease, and we need to tackle the disease before it becomes full blown in adulthood," said Dr. Molleston. "We routinely test children for conditions with much lower incidence such as scoliosis. Although we do not yet have formal guidelines for screening for Fatty Liver Disease, I personally think that all obese children should be screened for Fatty Liver Disease so we can intervene before it damages the liver."
“我们观察到患脂肪肝的年轻人的数目正在不断增加，并且我们需要控制这种疾病避免成年时完全发展。“Molleston说。”我们以某些发生率很低的疾病为条件定期检查孩子如脊柱侧凸。虽然我们仍没为筛选脂肪肝提供正式指南，但是我个人认为为了我们能在它损坏肝脏之前干预，所有过度肥胖的儿童应该被认为患脂肪肝。

A simple blood test to determine if liver enzyme levels are elevated alerts pediatricians that the child needs to be evaluated for Fatty Liver Disease.
简单的验血为确定如果肝酶水平升高，则提醒儿科医师儿童需要被评估为患脂肪肝。

Approximately a third of children and teens in the United States are overweight and 15% of children and teens are obese. Fatty Liver Disease may exist in 15% or more of obese children.

在美国近三分之一的儿童和青少年超重，并且这其中有15%极度肥胖。这15%或更多的极度肥胖儿童也许存在脂肪肝。

The American Liver Foundation estimates that 10-20% of Americans have Fatty Liver Disease.
美国肝脏基金会评估10-20%美国人有脂肪肝。

2007-03-17 22:31

投票
收藏
打赏
引用
分享
- 微信扫一扫
- 新浪微博
- 丁香客
- 复制网址
举报
- 广告宣传推广
- 政治敏感、违法虚假信息
- 恶意灌水、重复发帖
- 违规侵权、站友争执
- 附件异常、链接失效
- 其他

• 2021中级内科303题目回顾（随时更新）

jie20088

丁香园准中级站友

4楼

编译：
字数646

http://www.eurekalert.org/pub_releases/2007-03/iu-iof031507.php

公开发行日期：2007年3月15日
肥胖儿童的脂肪肝发生率有所升高
印第安纳波利斯——印第安纳大学医学院研究员对一种随着儿童肥胖度增加发生率升高的疾病进行了仔细的观察。非酒精性脂肪性肝，更普遍以脂肪肝著称，在极度肥胖的儿童中发生率大约15%。脂肪肝即脂肪在肝脏中积聚，儿时没有生命威胁，成年后可能导致肝硬化，有时还需要肝移植。
“到目前，对脂肪肝的唯一治疗是提供饮食和锻炼的建议，但是这经常是无效的。作为国际多渠道研究网络的一部分，我们当前正在关注维生素E和甲福明二甲双胍（一种治疗2型糖尿病的药物）作为可能的疗法。”身为IU（印第安纳大学）医学院儿科临床教授以及Riley医院儿科肠胃病学主管的Molleston, M.D如是说。Molleston博士是IU医学院开展的名为“ site of TONIC”项目的项目负责人。这个项目由国家糖尿病、消化系统与肾病研究院（the National Institute of Diabetes and Digestive and Kidney Disease）资助的8中心的三期研究，其目的是研究8-17岁的青少年脂肪肝的医疗方法，这是迄今为止同类研究中规模最大的一个。
“我们观察到患脂肪肝的年轻人的数目正在不断增加，并且我们需要控制这种疾病避免成年时完全发展。“Molleston说。”我们以某些发生率很低的疾病为条件定期检查孩子如脊柱侧凸。虽然我们仍没为筛选脂肪肝提供正式指南，但是我个人认为为了我们能在它损坏肝脏之前干预，所有过度肥胖的儿童应该被认为患脂肪肝。
简单的验血为确定如果肝酶水平升高，则提醒儿科医师儿童需要被评估为患脂肪肝。
在美国近三分之一的儿童和青少年超重，并且这其中有15%极度肥胖。这15%或更多的极度肥胖儿童也许存在脂肪肝。
美国肝脏基金会评估10-20%美国人有脂肪肝。

2007-03-17 22:35

投票
收藏
打赏
引用
分享
- 微信扫一扫
- 新浪微博
- 丁香客
- 复制网址
举报
- 广告宣传推广
- 政治敏感、违法虚假信息
- 恶意灌水、重复发帖
- 违规侵权、站友争执
- 附件异常、链接失效
- 其他

• 2021【儿科】中级考试集结地，欢迎讨论你的考后感受！

科技动态

【medical-news】肥胖儿童的脂肪肝发生率有所升高

提示

丁香园旗下网站

关于丁香园

官方链接

科技动态

分享到：

微信扫一扫

【medical-news】肥胖儿童的脂肪肝发生率有所升高

微信扫一扫

微信扫一扫

微信扫一扫

微信扫一扫

提示

丁香园旗下网站

关于丁香园

官方链接