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【每日动态】每日生物医药科技动态汇编 2015年5月

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每日生物医药科技动态汇编2015年5月1日
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http://news.dxy.cn/bbs/topic/2140938

Public Release: 1-May-2015
How to reset a diseased cell
UNIVERSITY OF CALIFORNIA - SAN DIEGO
In proof-of-concept experiments, researchers at University of California, San Diego School of Medicine demonstrate the ability to tune medically relevant cell behaviors by manipulating a key hub in cell communication networks. The manipulation of this communication node, reported in this week's issue of Proceedings of the National Academy of Sciences, makes it possible to reprogram large parts of a cell's signaling network instead of targeting only a single receptor or cell signaling pathway.
JOURNALProceedings of the National Academy of SciencesFUNDERNational Institutes of Health, American Cancer Society, Burroughs Wellcome Fund, Dorris Duke Charitable Foundation, American Heart AssociationPublic Release: 1-May-2015
First-year undergrad identifies method to potentially save money in health care
UNIVERSITY OF CHICAGO
Nationwide implementation of the American College of Cardiology's appropriate use criteria could result in a cost savings of more than $2.3 billion, based on a two-year study of a community hospital in Illinois.
MEETINGAmerican College of Cardiology Annual Scientific Session

Public Release: 1-May-2015
A feel for flight: How bats are teaching scientists to build better aircraft
COLUMBIA UNIVERSITY MEDICAL CENTER
Researchers have studied how bats can sense their environment using neural cells connected to their wings. This makes them amazing flyers, able to adapt to a variety of challenging situations. By understanding the neuroscience of bat flight, scientists are also learning how to design smarter and better planes.
JOURNALCell ReportsFUNDERNational Institutes of Health

Public Release: 1-May-2015
Beetlejuice! Secrets of beetle sprays unlocked at the Advanced Photon Source
DOE/ARGONNE NATIONAL LABORATORY
Researchers using the Advanced Photon Source, a US Department of Energy user facility at Argonne National Laboratory, have gotten the first-ever look inside the living beetle as it sprays. The results are published today in Science.
JOURNALScienceFUNDERUS Army Research Laboratory, US Army Research Office/MIT Institute of Soldier Nanotechnologies, National Science Foundation, US Department of Defense, US Department of Energy's Office of SciencePublic Release: 1-May-2015
Majority of older adults willing to be screened by telephone for dementia
INDIANA UNIVERSITY
Nearly two-thirds of older adults were willing to undergo telephone screening for dementia, according to a new study from the Indiana University Center for Aging Research and the Regenstrief Institute. Willingness to be screened by phone did not differ by sex, age or race.
JOURNALJournal of Aging ResearchFUNDERNIH/National Institute on AgingPublic Release: 1-May-2015
New gene editing tools force renewed debate over therapeutic germline alteration
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS
Recent evidence demonstrating the feasibility of using novel CRISPR/Cas9 gene editing technology to make targeted changes in the DNA of human embryos is forcing researchers, clinicians, and ethicists to revisit the highly controversial issue of altering the inherited human genome. A provocative Editorial exploring the current technical limitations, safety concerns, and moral acceptability of therapeutic germline gene editing is published in Human Gene Therapy.
JOURNALHuman Gene TherapyPublic Release: 1-May-2015
Beyond chicken fingers & fries: New evidence in favor of healthier kids' menus
SOCIETY FOR MATERNAL-FETAL MEDICINE
New research in Obesity is first of its kind to look at ordering patterns and sales data following healthy menu changes.
JOURNALObesityPublic Release: 1-May-2015
Use wipes in the kitchen to reduce risk of food poisoning by 99 percent
WILEY
Consumers can reduce the risk of Campylobacter food poisoning by up to 99.2 percent by using disinfectant wipes in the kitchen after preparing poultry.
JOURNALJournal of Applied MicrobiologyPublic Release: 1-May-2015
A practical gel that simply 'clicks' for biomedical applications
WYSS INSTITUTE FOR BIOLOGICALLY INSPIRED ENGINEERING AT HARVARD
Wyss Core Faculty members Neel Joshi, Ph.D., and David Mooney, Ph.D., have developed a novel, truly biocompatible alginate hydrogel that can be synthesized using 'click chemistry' towards better delivery of drugs, growth factors and living cells for biomedical applications. The gel is formed using chemical crosslinking strategies that allow engineers to entrap cells or molecules inside the gel without damaging them or rendering them inactive.
JOURNALBiomaterialsPublic Release: 1-May-2015
UNC researchers create DNA repair map of the entire human genome
UNIVERSITY OF NORTH CAROLINA HEALTH CARE
When common chemotherapy drugs hit cancer cells, they damage DNA so that the cells can't replicate. But the cells have ways to repair the DNA, and the drugs aren't effective enough. UNC researchers created a way to find where this DNA repair happens throughout all of human DNA. The finding offers scientists a route to target the proteins cancer cells use to circumnavigate therapy. The benefit could be more effective and better cancer therapeutics.
JOURNALGenes & Development

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2015-05-01 07:43 浏览 : 19110 回复 : 32

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freelane 编辑于 2015-05-03 22:21

• 吴艳教授：痤疮及其瘢痕治疗新进展

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每日生物医药科技动态汇编 2015年5月2日
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Public Release: 1-May-2015
Parent training reduces serious behavioral problems in children with autism
Yale University
Young children with autism spectrum disorder, who also have serious behavioral problems, showed improved behavior when their parents were trained with specific, structured strategies to manage tantrums, aggression, self-injury, and non-compliance. The findings from this parent training study by Yale and Emory University researchers were published recently in the Journal of the American Medical Association.
JournalJAMAFunderNIH/National Institute of Mental Health, NIH/National Center for Advancing Translational Sciences, Marcus Foundation, Joseph B. Whitehead Foundation, and others Public Release: 1-May-2015
Ocean fronts improve climate and fishery production, study finds
University of Georgia
A recent study by the University of Georgia found that ocean fronts -- separate regions of warm and cool water as well as salt and fresh water -- act to increase production in the ocean. Brock Woodson's research, published in the Proceedings of the National Academy of Sciences, showed how fronts can be incorporated into current climate and fisheries models to account for small-scale interactions in fishery production and cycling of elements such as carbon and nitrogen in the ocean.
JournalProceedings of the National Academy of Sciences Public Release: 1-May-2015
Lousy sockeye are lousy competitors
Simon Fraser University
With major funding from several groups, including NSERC, an SFU doctoral student has made a key discovery regarding Fraser River sockeye's vulnerability to sea lice. Their recently published research indicates that juvenile Fraser River sockeye salmon that are highly infected with sea lice are 20 percent less successful at consuming food than their lightly infected counterparts. The study appears online in the Canadian Journal of Fisheries and Aquatic Sciences.
JournalCanadian Journal of Fisheries and Aquatic SciencesFunderNatural Sciences and Engineering Research Council of Canada Public Release: 1-May-2015
Mixing energy drinks, alcohol tied to abusive drinking in teens
The Geisel School of Medicine at Dartmouth
Researchers from Dartmouth's Norris Cotton Cancer Center found teens aged 15-17 years old who had ever mixed alcohol with energy drinks were four times more likely to meet the criteria for alcohol use disorder than a teen who has tried alcohol but never mixed it with an energy drink.
JournalJournal of PediatricsFunderNational Institutes of Health Public Release: 1-May-2015
TGen-UCSF study in Neuro-Oncology provides comprehensive look at brain cancer treatments
The Translational Genomics Research Institute
Led by TGen and UCSF, a comprehensive genetic review of treatment strategies for glioblastoma brain tumors was published today in the Oxford University Press journal Neuro-Oncology. The study, 'Towards Precision Medicine in Glioblastoma: The Promise and The Challenges', covers how these highly invasive and almost-always-deadly brain cancers may be treated, reviews the continuing challenges faced by researchers and clinicians, and presents the hope for better treatments by harnessing the power of the human genome.
JournalNeuro-Oncology
Public Release: 1-May-2015
Majority of older adults willing to be screened by telephone for dementia
Indiana University
Nearly two-thirds of older adults were willing to undergo telephone screening for dementia, according to a new study from the Indiana University Center for Aging Research and the Regenstrief Institute. Willingness to be screened by phone did not differ by sex, age or race.
JournalJournal of Aging ResearchFunderNIH/National Institute on Aging
Public Release: 1-May-2015
New gene editing tools force renewed debate over therapeutic germline alteration
Mary Ann Liebert, Inc./Genetic Engineering News
Recent evidence demonstrating the feasibility of using novel CRISPR/Cas9 gene editing technology to make targeted changes in the DNA of human embryos is forcing researchers, clinicians, and ethicists to revisit the highly controversial issue of altering the inherited human genome. A provocative Editorial exploring the current technical limitations, safety concerns, and moral acceptability of therapeutic germline gene editing is published in Human Gene Therapy.
JournalHuman Gene Therapy
Public Release: 1-May-2015
Beyond chicken fingers & fries: New evidence in favor of healthier kids' menus
Society for Maternal-Fetal Medicine
New research in Obesity is first of its kind to look at ordering patterns and sales data following healthy menu changes.
JournalObesity
Public Release: 1-May-2015
Use wipes in the kitchen to reduce risk of food poisoning by 99 percent
Wiley
Consumers can reduce the risk of Campylobacter food poisoning by up to 99.2 percent by using disinfectant wipes in the kitchen after preparing poultry.
JournalJournal of Applied Microbiology
Public Release: 1-May-2015
A practical gel that simply 'clicks' for biomedical applications
Wyss Institute for Biologically Inspired Engineering at Harvard
Wyss Core Faculty members Neel Joshi, Ph.D., and David Mooney, Ph.D., have developed a novel, truly biocompatible alginate hydrogel that can be synthesized using 'click chemistry' towards better delivery of drugs, growth factors and living cells for biomedical applications. The gel is formed using chemical crosslinking strategies that allow engineers to entrap cells or molecules inside the gel without damaging them or rendering them inactive.
JournalBiomaterials
Public Release: 1-May-2015
UNC researchers create DNA repair map of the entire human genome
University of North Carolina Health Care
When common chemotherapy drugs hit cancer cells, they damage DNA so that the cells can't replicate. But the cells have ways to repair the DNA, and the drugs aren't effective enough. UNC researchers created a way to find where this DNA repair happens throughout all of human DNA. The finding offers scientists a route to target the proteins cancer cells use to circumnavigate therapy. The benefit could be more effective and better cancer therapeutics.
JournalGenes & DevelopmentFunderNational Institutes of Health
Public Release: 1-May-2015
The ER docs said 'stop smoking,' and they did!
American College of Emergency Physicians
An intervention in the emergency department designed to encourage tobacco cessation in smokers appears to be effective. Two and a half times more patients in the intervention group were tobacco-free three months after receiving interventions than those who did not receive the interventions, according to a study published online Friday in Annals of Emergency Medicine.
JournalAnnals of Emergency Medicine
Public Release: 1-May-2015
Study finds guidance improves food safety practices at school, community gardens
North Carolina State University
School and community gardens have become increasingly popular in recent years, but the people managing and working in these gardens are often unfamiliar with food safety practices that reduce the risk of foodborne illness. Now researchers have developed guidelines that address how to limit risk in these gardens -- and a pilot study shows that the guidelines make a difference.
JournalFood Protection TrendsFunderNorth Carolina Department of Instruction, North Carolina Recreation and Parks Association, Carolina Center for Public Service
Public Release: 1-May-2015
Lifetime intense physical activity may lower risk for non-Hodgkin lymphoma
American Association for Cancer Research
Performing vigorous physical activity over one's lifetime may lower risk for non-Hodgkin lymphoma.
JournalCancer Epidemiology, Biomarkers & PreventionFunderCanadian Cancer Society, Canadian Institutes of Health Research
Public Release: 1-May-2015
Prolonged statin use may lower risk of lung cancer death
American Association for Cancer Research
Lung cancer patients who used statins in the year prior to a lung cancer diagnosis or after a lung cancer diagnosis had a reduction in the risk of death from the disease.
JournalCancer Epidemiology, Biomarkers & PreventionFunderHealth and Social Care Research, Development Division of the Public Health Agency of Northern Ireland

2015-05-02 21:05

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freelane 编辑于 2015-05-03 22:20

• 基层年轻医生该如何提高技术

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2015-05-03 11:16

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• 基层年轻医生该如何提高技术

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每日生物医药科技动态汇编 2015年5月4日

Public Release: 4-May-2015
'Fuzzy thinking' in depression & bipolar disorder: New research finds effect is real
UNIVERSITY OF MICHIGAN HEALTH SYSTEM
People with depression or bipolar disorder often feel their thinking ability has gotten 'fuzzy', or less sharp than before their symptoms began. Now, researchers have shown in a very large study that effect is indeed real -- and rooted in brain activity differences that show up on advanced brain scans.
JOURNALBrainFUNDERNational Alliance for Research on Schizophrenia and Depression, NIH/National Institute of Mental Health, University of Michigan Department of Psychiatry Research Committee and fMRI lab, Heinz C. Prechter Bipolar Research Fund at the U-M Depression Center
Public Release: 4-May-2015
Enhancing emergency medical care for seniors could reduce hospital admissions
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE
Applying palliative care principles to emergency departments may reduce the number of geriatric patients admitted to intensive care units.
JOURNALHealth AffairsFUNDERCenters for Medicare and Medicaid Services
Public Release: 4-May-2015
Scientists find new link between diabetes and Alzheimer's
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Researchers have uncovered a unique connection between diabetes and Alzheimer's disease, providing further evidence that a disease that robs people of their memories may be affected by elevated blood sugar, according to scientists at Washington University School of Medicine in St. Louis.
JOURNALJournal of Clinical Investigation
Public Release: 4-May-2015
Recurrence of prostate cancer detected earlier with innovative PSMA-ligand PET/CT
SOCIETY OF NUCLEAR MEDICINE
A recent study reported in The Journal of Nuclear Medicine compared use of the novel Ga-68-PSMA-ligand PET/CT with other imaging methods and found that it had substantially higher detection rates of prostate-specific membrane antigen in patients with biochemical recurrence after radical prostatectomy. It is especially noteworthy that this hybrid PSMA-ligand identified a large number of positive findings in the clinically important range of low PSA-values (<0.5ng/mL).
JOURNALJournal of Nuclear MedicineFUNDEREuropean Union Seventh Framework Program

Public Release: 4-May-2015
UNC Team uses cellular bubbles to deliver Parkinson's meds directly to brain
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
Exosomes could help with longstanding medical issues from cancer diagnosis to sophisticated research tool. Now, they could potentially help with delivering potent antioxidants into the brain of Parkinson's patients.
JOURNALJournal of Controlled ReleaseFUNDERNational Institutes of Health, Ministry of Education and Science of Russian Federation
Public Release: 4-May-2015
May 2015 Gastrointestinal Endoscopy highlights
AMERICAN SOCIETY FOR GASTROINTESTINAL ENDOSCOPY
The May issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy, features a meta-analysis pointing to botulinum toxin A as a possible obesity treatment; a study reporting that, in some cases, it may be safe to store endoscopes longer than five days after reprocessing; and an article reviewing a promising group of procedures for patients with advanced illness from gastric obstruction.
JOURNALGastrointestinal EndoscopyFUNDERMedical University of South Carolina

Public Release: 4-May-2015
Puget Sound's clingfish could inspire better medical devices, whale tags
UNIVERSITY OF WASHINGTON
Researchers at the University of Washington's Friday Harbor Laboratories are looking at how the biomechanics of clingfish could be helpful in designing devices and instruments to be used in surgery and even to tag and track whales in the ocean.
MEETING2015 Adhesive and Sealant Council Annual MeetingFUNDERNational Science Foundation, The Seaver Foundation
Public Release: 4-May-2015
3-D printed trachea among key Mount Sinai research presented at AATS meeting
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE
Icahn School of Medicine at Mount Sinai researchers presented several landmark studies at the 2015 American Association for Thoracic Surgery meeting in Seattle.
MEETINGAmerican Association for Thoracic Surgery 2015 Annual Meeting
Public Release: 4-May-2015
Detecting knee-cushion problems early could lead to better treatments
UNIVERSITY OF MISSOURI-COLUMBIA
The menisci, best known as the shock absorbers in the knee, help disperse pressure, reduce friction and nourish the knee. Now, new research from the University of Missouri shows even small changes in the menisci can hinder their ability to perform critical knee functions.

Public Release: 4-May-2015
Moderate exercise may make cancer treatments more effective, kinesiologist finds
KANSAS STATE UNIVERSITY
Kansas State University kinesiology research offers encouraging information for cancer patients: A brisk walk or a slow jog on a regular basis may be the key to improved cancer treatments.
FUNDERAmerican Cancer Society
Public Release: 4-May-2015
Discovery could help reverse glucocorticoid resistance in some young leukemia patients
ST. JUDE CHILDREN'S RESEARCH HOSPITAL
Researchers led by St. Jude Children's Research Hospital scientists have identified a mechanism that helps leukemia cells resist glucocorticoids, a finding that lays the foundation for more effective treatment of cancer and possibly a host of autoimmune diseases.
JOURNALNature GeneticsFUNDERNational Institutes of Health; American Recovery and Reinvestment Act supplement; American Lebanese Syrian Associated Charities
Public Release: 4-May-2015
Green tea extract and exercise hinder progress of Alzheimer's disease in mice
UNIVERSITY OF MISSOURI-COLUMBIA
According to the National Institutes of Health, Alzheimer's disease may affect as many as 5.5 million Americans. Scientists currently are seeking treatments and therapies found in common foods that will help stave off the disease or prevent it completely. Now, University of Missouri researchers have determined that a compound found in green tea, and voluntary exercise, slows the progression of the disease in mice and may reverse its effects.
JOURNALJournal of Alzheimer's DiseaseFUNDERNational Institute of Aging
Public Release: 4-May-2015
Scientists dramatically improve method for finding common genetic alterations in tumors
ST. JUDE CHILDREN'S RESEARCH HOSPITAL
St. Jude Children's Research Hospital scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome sequencing. The findings appear today in the scientific journal Nature Methods.
JOURNALNature MethodsFUNDERPediatric Cancer Genome Project, Kay Jewelers, NIH/National Cancer Institute, and ALSAC
Public Release: 4-May-2015
Youth just as likely to try e-cigarettes as smoking
UNIVERSITY OF WATERLOO
Young people are just as likely to try electronic cigarettes as smoking, according to a new report from the Propel Centre for Population Health Impact at the University of Waterloo.

Public Release: 4-May-2015
Personal cues can have a strong effect on craving in individuals with addiction
WILEY
Unique person-specific cues -- such as the presence of a specific friend or hearing a specific song -- appear to have a robust effect on craving addictive substances, a recent study shows. The study also found that person-specific cues may have a longer effect on craving than more general substance-specific cues, such as the presence of bottles, syringes, or lighters.
JOURNALAddiction
Public Release: 4-May-2015
Weight loss may increase risk of premature death in patients with rheumatoid arthritis
WILEY
In contrast to the general population, low body mass index has been associated with premature death in patients with rheumatoid arthritis -- a situation known as the 'obesity paradox.' A new Arthritis & Rheumatology study shows that weight loss, as opposed to low body mass index per se, is a strong predictor of mortality in these patients.
JOURNALArthritis & Rheumatology
Public Release: 4-May-2015
Study identifies desire and arousal as the main players in women's sexual health
WILEY
In a 4-year study of 178 pre- and 329 postmenopausal women, investigators found that women's sexual functioning was moderately stable over time. The main predictors of changes in sexual functioning and satisfaction were desire and arousal, highlighting their role as the main 'players' in women's sexual health.
JOURNALThe Journal of Sexual Medicine
Public Release: 4-May-2015
UTMB study shows cost-effective expert recommended asthma test underutilized by physicians
UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON
Researchers from the University of Texas Medical Branch at Galveston have found, for the first time, that spirometry was underutilized for asthma diagnosis and management in US adults from 2001 to 2011, despite it's accuracy, cost effectiveness and the publication of national guidelines advocating its use.
JOURNALAmerican Journal of MedicineFUNDERUniversity of Texas Systems Health IT and Systems Engineering

Public Release: 4-May-2015
Odd histone helps suppress jumping genes in stem cells, study says
ROCKEFELLER UNIVERSITY
Research begun at Rockefeller University has uncovered a purpose for a rare type of histone: preventing mutations by keeping certain so-called 'jumping genes' in place. This discovery reveals a basic mechanism for epigenetics, or the control of inherited traits through means other than DNA.

2015-05-06 16:01

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freelane 编辑于 2015-05-06 16:08

• 基层年轻医生该如何提高技术

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