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【每日动态】每日生物医药科技动态汇编2015年10月

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每日生物医药科技动态汇编2015年10月
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2015-10-01 20:35 来自 Android客户端浏览 : 2971 回复 : 33

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freelane 编辑于 2015-10-01 22:56

• 常见药物有哪些需注意的配伍禁忌？

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每日生物医药科技动态汇编2015年10月2日
Public Release: 2-Oct-2015
A stand-up solution
UNIVERSITY OF IOWA
According to a new University of Iowa study, employees with sit-stand desks stood 60 minutes more a day at work compared with their co-workers with sitting desks, and they continued to do so long after their newfangled desks lost their novelty.
JOURNALAmerican Journal of Preventive MedicineFUNDERUniversity of Iowa Division of Sponsored ProgramsPublic Release: 2-Oct-2015
Drug used to treat cancer appears to sharpen memory
RUTGERS UNIVERSITY
A drug now being used to treat cancer might make it easier to learn a language, sharpen memory and help those with dementia and Alzheimer's disease by rewiring the brain and keeping neurons alive. New Rutgers research found that a drug -- RGFP966 -- administered to rats made them more attuned to what they were hearing, able to retain and remember more information, and develop new connections that allowed these memories to be transmitted between brain cells.
JOURNALJournal of NeurosciencePublic Release: 2-Oct-2015
Exercise is good for everyone -- but some struggle more than others
LUND UNIVERSITY
People with increased risk of type 2 diabetes need to exercise more than others to achieve the same results, according to new research from Lund University in Sweden.
JOURNALJournal of Applied PhysiologyPublic Release: 2-Oct-2015
Studying cardiac arrhythmias in nematodes
GOETHE UNIVERSITY FRANKFURT
Researchers at the Goethe University have developed a simple model using the nematode Caenorhabditis elegans that can be used to test substances for treating genetically mediated cardiac arrhythmias.
JOURNALScientific ReportsPublic Release: 2-Oct-2015
First-aid for defective mucus
TECHNICAL UNIVERSITY OF MUNICH (TUM)
Proper lubrication is crucial to keep not only machines but also humans functioning smoothly. The mucus membranes in our mouths, eyes, stomachs and genital area help keep friction to a minimum and also protect us against environmental hazards such as chemicals and pathogens. Professor Oliver Lieleg and his working group at the Institute of Medical Technology at TUM are investigating exactly how these mechanisms work.
JOURNALAdvanced Material InterfacesPublic Release: 2-Oct-2015
JAX reseachers, collaborators report on variations in human genome
JACKSON LABORATORY
A consortium of international researchers, including Charles Lee, Ph.D., of The Jackson Laboratory for Genomic Medicine, have reported findings from a massive research project exploring variations in the human genome, including structural variations.
JOURNALNatureFUNDERNational Institutes of Health

Public Release: 2-Oct-2015
Big eyes!
MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE IN THE HELMHOLTZ ASSOCIATION
'Why, Grandma, what big eyes you have!' Though similar in appearance, the hidden cause of those big eyes Little Red Riding Hood notices in Grimms' fairy tale has nothing to do with the hidden cause of enlarged eyeballs in buphthalmia, a genetic mechanism causing this devastating eye disease which has now been uncovered by researchers from the Max Delbrück Center Medicine for Molecular Medicine. Patients afflicted are severely myopic, or nearsighted.
JOURNALDevelopmental CellFUNDERDFG/Sonderforschungsbereich Collaborative Research Centre, Helmholtz Association/HGF Postdoctoral Fellowship ProgramPublic Release: 2-Oct-2015
International agreement on MRI-scans 'likely to change how we detect prostate cancer'
EUROPEAN ASSOCIATION OF UROLOGY
International radiological bodies have agreed on a standard for how doctors evaluate MRI to confirm a diagnosis of prostate cancer. This promises to reduce the number of over diagnosis of insignificant cancers by to up to 89 percent. The new procedure also allows radiologists to identify up to 13 percent more life-threatening tumors than current procedures.
JOURNALEuropean Urology

Public Release: 2-Oct-2015
A novel technology to produce microalgae biomass as feedstock for biofuel, food, feed and more
WORLD SCIENTIFIC
Novel and scalable technology and production process combining algal biomass cultivation, harvesting and concentration as well as extraction and fractionation of fatty acids from the biomass results in ability to offer high quality feedstock for various industries in a highly competitive price.
JOURNALTechnology

Public Release: 2-Oct-2015
Pneumothorax treatment gets less painful
WORLD SCIENTIFIC
Scientists working in Tianjin Chest Hospital, China, have developed a less painful treatment strategy for Pneumothorax treatment. By analyzing the partial pressure of oxygen and carbon dioxide in thoracic cavity gas during Pneumothorax Treatment, physicians can understand the real conditions of the pneumothorax and then update to a less painful treatment method.
JOURNALTechnology

Public Release: 2-Oct-2015
High-fructose diet slows recovery from brain injury
UNIVERSITY OF CALIFORNIA - LOS ANGELES HEALTH SCIENCES
A diet high in processed fructose sabotages rat brains' ability to heal after head trauma, UCLA neuroscientists report. Revealing a link between nutrition and brain health, the finding offers implications for the 5.3 million Americans living with a traumatic brain injury, or TBI.
JOURNALJournal of Cerebral Blood Flow and MetabolismFUNDERNIH/National Institute of Neurological Disorders and Stroke, National Center for Research Resources
Public Release: 1-Oct-2015
Research links built characteristics of environment with health of persons with SCI
KESSLER FOUNDATION
Scientists in disability outcomes research have determined that differences in the built characteristics of communities may influence the health and wellbeing of residents with chronic spinal cord injury. communities with more heterogeneous land use was less beneficial to their perceived health. Based on survey data from the federally funded Spinal Cord Injury System database (n=503) and Geographic Information Systems data.
JOURNALArchives of Physical Medicine and RehabilitationFUNDERNIh/National Institute of Child Health and Development, NIh/National Institute for Disability Independent Living and Rehabilitation Research
Public Release: 1-Oct-2015
Late bedtimes could lead to weight gain
UNIVERSITY OF CALIFORNIA - BERKELEY
Teenagers and adults who go to bed late on weeknights are more likely to gain weight than their peers who hit the hay earlier, according to a UC Berkeley study that has found a correlation between sleep and body mass index.
JOURNALSleepFUNDERNational Science Foundation, NIH/National Institute of Mental Health
Public Release: 1-Oct-2015
Penn Vet-Temple team characterizes genetic mutations linked to a form of blindness
UNIVERSITY OF PENNSYLVANIA
A collaboration between University of Pennsylvania and Temple University scientists has identified two naturally occurring genetic mutations in dogs that result in achromatopsia, a form of blindness.
JOURNALPLOS ONEFUNDERFoundation Fighting Blindness, NIH/National Eye Institute, National Science Foundation, European Union Seventh Framework Program, Hope for Vision, Macula Vision Research Foundation, Van Sloun Fund for Canine Genetic Research

Public Release: 1-Oct-2015
Fatty liver disease and scarring have strong genetic component
UNIVERSITY OF CALIFORNIA - SAN DIEGO
Researchers at the University of California, San Diego School of Medicine say that hepatic fibrosis, which involves scarring of the liver that can result in dysfunction and, in severe cases, cirrhosis and cancer, may be as much a consequence of genetics as environmental factors.
JOURNALGastroenterologyFUNDERAmerican Gastroenterological Association Foundation, T. Franklin Williams Scholarship Award, Atlantic Philanthropies, Inc., John A. Hartford Foundation, Association of Specialty Professors and the American Gastroenterological Association
Public Release: 1-Oct-2015
Research shows a cause of gastrointestinal symptoms in Type 1 diabetes
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO
Research published today provides a molecular basis for why 80 percent of patients with longstanding Type 1 diabetes have chronic gastrointestinal symptoms including gastroparesis (delayed emptying of food), irritable bowel syndrome, abdominal distension and fecal incontinence, significantly reducing their quality of life. Studies included an author from the School of Medicine at The University of Texas Health Science Center at San Antonio.
JOURNALCell Stem Cell
Public Release: 1-Oct-2015
Study finds gaps in clinical genetic counseling services for women undergoing BRCA testing
UNIVERSITY OF SOUTH FLORIDA (USF HEALTH)
A University of South Florida-led research collaboration with Aetna, the American Cancer Society and the national non-profit Facing Our Risk of Cancer Empowered today published results from a national study identifying factors and outcomes associated with the use of genetic counseling and testing services for hereditary breast and ovarian cancer in the community setting. The work indicates a significant opportunity to increase genetic counseling in community care.
JOURNALJAMA OncologyFUNDERAetna Foundation, USF, Facing Our Risk of Cancer Empowered, Inc (FORCE), American Cancer Society
Public Release: 1-Oct-2015
Blueprints for limbs encoded in the snake genome
UNIVERSITY OF GEORGIA
When researchers at the University of Georgia examined the genome of several different snake species, they found something surprising. Embedded in reptiles' genetic code was DNA that, in most animals, controls the development and growth of limbs -- a strange feature for creatures that are famous for their long, legless bodies and distinctive slither. Now, they've found an explanation.
JOURNALDevelopmental CellFUNDERNational Institutes of Health, University of Georgia

Public Release: 1-Oct-2015
Tissue-engineered colon from human cells develop different types of neurons
CHILDREN'S HOSPITAL LOS ANGELES
A study by scientists at Children's Hospital Los Angeles has shown that tissue-engineered colon derived from human cells is able to develop the many specialized nerves required for function, mimicking the neuronal population found in native colon. These specialized neurons, localized in the gut, form the enteric nervous system, which regulates digestive tract motility, secretion, absorption and gastrointestinal blood flow.
JOURNALTissue Engineering, Part AFUNDERCalifornia Institute of Regenerative Medicine, NIH/National Institute of Diabetes, Digestive and Kidney Diseases
Public Release: 1-Oct-2015
Gene therapy doubles survival in recurrent glioblastoma
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO
An experimental gene therapy essentially doubled the overall survival of patients with recurrent glioblastoma compared to the current standard of care, a researcher said Oct. 1 at the Cancer Therapy & Research Center at The University of Texas Health Science Center at San Antonio.
MEETING18th ECCO - 40th ESMO European Cancer Congress

2015-10-02 09:32

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freelane 编辑于 2015-10-02 23:26

• 【丁香面试直通车】72小时急速反馈内推直达简历优化面试辅导

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每日生物医药科技动态汇编2015年10月3日
Medicine & Health
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Public Release: 2-Oct-2015
Researchers discover evidence that lead exposure in mothers can affect future generation
WAYNE STATE UNIVERSITY - OFFICE OF THE VICE PRESIDENT FOR RESEARCH
A team of researchers at Wayne State University have discovered that mothers with high levels of lead in their blood not only affect the fetal cells of their unborn children, but also their grandchildren. Their study, Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren, was published online this week in Scientific Reports.
JOURNALScientific ReportsFUNDERNIH/National Institute of Environmental Health Sciences, University Research Corridor
Public Release: 2-Oct-2015
Scientists closer to controlling body temperature in response to 'fight or flight'
FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY
New research published online in The FASEB Journal suggests that the fight or flight response that we experience in stressful situations may be controlled by a protein called TRPV1. In the mouse study, researchers found that TRPV1 controls the nerves that release noradrenaline and affect core body temperature. This opens the doors for the development of new strategies to treat the effects of stress on the body.
JOURNALFASEB Journal
Public Release: 2-Oct-2015
Online e-cigarette vendors engage customers using popular internet tools
UNIVERSITY OF CALIFORNIA - SAN DIEGO
First introduced in the United States in 2007, electronic cigarettes have risen dramatically in part because they are popularly considered safer and more socially acceptable than combustible cigarettes and because there are fewer restrictions on their purchase and use. A study by University of California, San Diego School of Medicine researchers, published in the journal Drug and Alcohol Dependence, points to aggressive online marketing tactics that make purchasing e-cigarettes easy for all ages.
JOURNALDrug and Alcohol Dependence
Public Release: 2-Oct-2015
Researcher calls for changes to colorectal cancer screening guidelines
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE
Colorectal cancer will claim the lives of close to 50,000 Americans this year, according to the American Cancer Society. Screening is the most effective way to reduce the risk of dying from the disease, yet as a Penn Medicine physician argues in an editorial this week in the journal Gastroenterology, current recommendations to screen older people with a family history of colorectal cancer, specifically with colonoscopy every five years, is not justified for most patients.
JOURNALGastroenterology
Public Release: 2-Oct-2015
High opioid use in older people with COPD raises safety concerns
ST. MICHAEL'S HOSPITAL
Researchers are raising safety concerns about high rates of new opioid use among older adults with COPD, according to a study published today.
JOURNALBritish Journal of PharmacologyFUNDERLung Association-Canadian Thoracic Society National Grant Review/Grant-in-Aid

Public Release: 2-Oct-2015
Colorful caterpillar chemists
SMITHSONIAN TROPICAL RESEARCH INSTITUTE
Scientists at the Smithsonian Tropical Research Institute compared the diets of two caterpillar species, expecting the one that exclusively consumed plants containing toxic chemicals would more easily incorporate toxins into its body than the one with a broad diet. They found the opposite. The new finding flies in the face of a long-held theory that specialist insects are better adapted to use toxic plant chemicals than non-specialists.
JOURNALJournal of Chemical EcologyFUNDERNational Institutes of Health

Public Release: 2-Oct-2015
Reducing aeromedical transport for traumas saved money and lives
AMERICAN COLLEGE OF EMERGENCY PHYSICIANS
Changes to the trauma triage protocol in Maryland resulted in decreased use of helicopter transport for trauma patients and improved patient outcomes, saving lives and money. The results of a 11-year study of the impact of statewide field triage changes to Maryland's helicopter emergency medical services (HEMS) were published online Wednesday in Annals of Emergency Medicine: 'Maryland's Helicopter Emergency Medicine Services Experience from 2001-2011: System Improvements and Patients' Outcomes.'
JOURNALAnnals of Emergency Medicine
Public Release: 2-Oct-2015
Irrigation of cutaneous abscesses may not be necessary
AMERICAN COLLEGE OF EMERGENCY PHYSICIANS
A procedure commonly performed in emergency departments on cutaneous abscesses may not have any impact on the need for further interventions and therefore may not be necessary, according to a study published online Friday in Annals of Emergency Medicine: 'Irrigation of Cutaneous Abscesses Does Not Improve Treatment Success.'
JOURNALAnnals of Emergency Medicine

Public Release: 2-Oct-2015
A stand-up solution
UNIVERSITY OF IOWA
According to a new University of Iowa study, employees with sit-stand desks stood 60 minutes more a day at work compared with their co-workers with sitting desks, and they continued to do so long after their newfangled desks lost their novelty.
JOURNALAmerican Journal of Preventive MedicineFUNDERUniversity of Iowa Division of Sponsored Programs
Public Release: 2-Oct-2015
Drug used to treat cancer appears to sharpen memory
RUTGERS UNIVERSITY
A drug now being used to treat cancer might make it easier to learn a language, sharpen memory and help those with dementia and Alzheimer's disease by rewiring the brain and keeping neurons alive. New Rutgers research found that a drug -- RGFP966 -- administered to rats made them more attuned to what they were hearing, able to retain and remember more information, and develop new connections that allowed these memories to be transmitted between brain cells.
JOURNALJournal of Neuroscience

2015-10-02 23:24

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freelane 编辑于 2015-10-03 21:33

• 成人股骨头坏死临床诊疗指南(2016)

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每日生物医药科技动态汇编2015年10月5日

Public Release: 6-Oct-2015
Lack of D1 receptor leads to slowness of movements in Parkinson's disease
NATIONAL INSTITUTES OF NATURAL SCIENCES
Assistant Professor Satomi Chiken and Professor Atsushi Nambu from National Institute for Physiological Sciences, Dr. Asako Sato from Kitasato University, Professor Toshikuni Sasaoka from Niigata University, and their research team members have revealed that lack of dopamine transmission through D1 receptors disturbs information flow through the 'direct pathway' in the basal ganglia, and ends up in difficulty in initiating voluntary movements.
JOURNALCerebral Cortex
Public Release: 6-Oct-2015
FMT now available in capsule form: could this be the end of antibiotics in C. difficile?
UNITED EUROPEAN GASTROENTEROLOGY
A new capsule form of faecal microbiota transplantation (FMT) has raised hopes that this effective treatment for Clostridium difficile (C. difficile) infection and other bowel conditions might soon become mainstream.
MEETINGUEG Week 2015
Public Release: 6-Oct-2015
Routine use of laparoscopic surgery for rectal cancer still to be established
UNIVERSITY OF SYDNEY
A comparison of the surgical removal of rectal tumors by a laparoscopically assisted procedure and open surgery reveals that the case for routine use of laparoscopic procedures has not yet been established, according to a randomized control-trial study published today in the Journal of the American Medical Association.
JOURNALJAMAFUNDERColorectal Surgical Society of Australia, New Zealand Foundation, National Health and Medical Research Council of Australia
Public Release: 6-Oct-2015
Study questions benefit of exercise program following immobilization of ankle fracture
THE JAMA NETWORK JOURNALS
A supervised exercise program and self-management advice, like those commonly given with physical therapy, did not improve activity limitation or quality of life compared with advice alone after removal of immobilization for patients with an uncomplicated ankle fracture, according to a study in the Oct. 6 issue of JAMA.
JOURNALJAMA
Public Release: 6-Oct-2015
Findings do not support routine use of minimally invasive surgery for rectal cancer
THE JAMA NETWORK JOURNALS
Compared to open resection (surgical removal) for rectal cancer, minimally invasive laparoscopic-assisted resection did not provide better cancer outcomes, according to two studies in the Oct. 6 issue of JAMA.
JOURNALJAMA
Public Release: 6-Oct-2015
More women may have option to get IUD minutes after giving birth
UNIVERSITY OF MICHIGAN HEALTH SYSTEM
More women may have the option to get an intrauterine device or contraceptive implant immediately after delivering a baby, thanks to expanding Medicaid coverage around the country.
JOURNALContraceptionFUNDERRobert Wood Johnson Foundation Clinical Scholars
Public Release: 6-Oct-2015
Simulation training saves precious minutes in speeding the treatment of trauma patients
AMERICAN COLLEGE OF SURGEONS
To help trauma teams optimize a limited window of time after an emergency, trauma surgeons have developed a simulation training program that cuts precious minutes off evaluation times and gets trauma patients to medical imaging tests faster, investigators reported at the 2015 Clinical Congress of the American College of Surgeons.
JOURNALJournal of the American College of SurgeonsMEETINGAmerican College of Surgeons Clinical Congress 2015

Public Release: 6-Oct-2015
Older patients recover more slowly from concussion
RADIOLOGICAL SOCIETY OF NORTH AMERICA
Older individuals may have a more difficult time recovering from concussion, according to a new study.
JOURNALRadiologyFUNDERNational Science Council, Taiwan, Taipei Medical University

Public Release: 5-Oct-2015
Self-regulating corals protect their skeletons against ocean acidification
ARC CENTRE OF EXCELLENCE IN CORAL REEF STUDIES
Scientists from the ARC Centre of Excellence for Coral Reef Studies have found a species of coral living in a dynamic reef system, which is able to protect itself from the impact of ocean acidification.
JOURNALProceedings of the National Academy of SciencesFUNDERAustralian Research Council Centre of Excellence for Coral Reef Studies
Public Release: 5-Oct-2015
Dengue protein modulates human enzyme: Fuel for replication
PUBLICASE COMUNICAÇÃO CIENTÍFICA
A new study published in the Journal of Virology reveals that NS1, a nonstructural protein composing the replication machinery of the dengue virus, binds to a well-known human enzyme as a way to increase energy production to be used for viral replication.
JOURNALJournal of Virology

2015-10-04 21:46

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freelane 编辑于 2015-10-07 01:22

• 今日一位院长被刺12刀死亡，起因据悉只是200元欠费!

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每日生物医药科技动态汇编2015年10月6日

Public Release: 6-Oct-2015
Five things hospitals can do to improve outcomes of weekend surgeries
LOYOLA UNIVERSITY HEALTH SYSTEM
Patients who undergo surgeries on weekends experience longer hospital stays and higher mortality rates and readmissions. A new study identifies five things hospitals can do to overcome this 'weekend effect.'
JOURNALAnnals of Surgery
Public Release: 6-Oct-2015
Virus-drug combination shows improved effectiveness against brain tumor cells
UNIVERSITY OF FLORIDA
A rabbit virus currently being developed for cancer therapy can be paired with one of several existing drugs to deliver a more potent punch to a deadly type of brain tumor cell, researchers have found.
JOURNALNeuro-OncologyFUNDERV Foundation for Cancer Research, Terry Fox Foundation, National Institutes of Health

Public Release: 6-Oct-2015
Treatment for heparin-induced blood disorder revealed in structure of antibody complex
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE
A potential treatment for a serious clotting condition that can strike patients who receive heparin to treat or prevent blood clots may lie within reach by elucidating the structure of the protein complex at its root.
JOURNALNature CommunicationsFUNDERNIH/National Heart, Lung and Blood Institute
Public Release: 6-Oct-2015
Chapman University researches way to mathematically make something go viral on Facebook
CHAPMAN UNIVERSITY
Researchers at Chapman University have proposed a strategic approach for information spreading via Facebook using cancer screenings as a health intervention. They use Facebook to identify social clusters and opinion leaders and mathematically determine the best way to spread information, using health information as the subject.
JOURNALHealth CommunicationFUNDERChapman University
Public Release: 6-Oct-2015
Tolerant immune system increases cancer risk
GERMAN CANCER RESEARCH CENTER (DEUTSCHES KREBSFORSCHUNGSZENTRUM, DKFZ)
If peripheral immune tolerance is very distinct, the risk for lung cancer doubles, the risk for colon cancer increases by 60 percent, scientists from the German Cancer Research Center have now reported. They have shown for the first time that individual variations in immune tolerance have an impact on the development of specific types of cancer - long before the actual onset of the disease.
JOURNALJournal of the National Cancer Institute
Public Release: 6-Oct-2015
Vaginal microbes influence whether mucus can trap HIV virus
AMERICAN SOCIETY FOR MICROBIOLOGY
HIV particles are effectively trapped by the cervicovaginal mucus from women who harbor a particular vaginal bacteria species, Lactobacillus crispatus. The findings, published this week in mBio, an online open-access journal of the American Society for Microbiology, could lead to new ways to reduce or block vaginal transmission of HIV and other sexually transmitted infections.
JOURNALmBio

Public Release: 6-Oct-2015
How the brain's wiring leads to cognitive control
UNIVERSITY OF PENNSYLVANIA
By using structural imaging techniques to convert brain scans into 'wiring diagrams' of connections between brain regions, researchers used the structure of these neural networks to reveal the fundamental rules that govern which parts of the brain are most able to exert 'cognitive control' over thoughts and actions.
JOURNALNature CommunicationsFUNDERAlfred P. Sloan Foundation, US Army Research Office, National Science Foundation, Public Health Service
Public Release: 6-Oct-2015
Binghamton University professor fights cancer with hedgehogs
BINGHAMTON UNIVERSITY
A Binghamton University biochemist has discovered a new way to fight cancer, one that attacks only the cancer cells and promises fewer side effects. He hunts hedgehogs. Hedgehogs are proteins that help govern how cells develop. Normally, once a person reaches maturation, the hedgehogs turn off. But in some cancers -- prostate, pancreatic, ovarian and lung in particular -- the hedgehogs somehow turn back on, and force uncontrolled cell growth: cancer.
JOURNALJournal of Biological ChemistryFUNDERDepartment of Defense
Public Release: 6-Oct-2015
Cell's waste disposal system regulates body clock proteins
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE
Researchers have a new genome screen that has identified partner molecules of cell-waste disposal proteins. They applied their new method to identify other clock partners that target a multipurpose cell nucleus receptor for disposal.
JOURNALProceedings of the National Academy of SciencesFUNDERNational Institute of Mental Health P50 Conte Center, NIh/National Institute of Neurological Disorders and Stroke, NIh/National Institute of Minority Health and Health Disparities, NIH/National Institute General Medical Sciences

Public Release: 6-Oct-2015
Heavy internet use may put teens at risk for high blood pressure
HENRY FORD HEALTH SYSTEM
Teens who spend hours on the Internet may be at risk for high blood pressure, say researchers at Henry Ford Hospital in Detroit. In a study published in the Journal of School Nursing, researchers found that teens who spent at least 14 hours a week on the Internet had elevated blood pressure. Of 134 teens described by researchers as heavy Internet users, 26 had elevated blood pressure.

Public Release: 6-Oct-2015
Flu vaccine helps reduce hospitalizations due to influenza pneumonia
VANDERBILT UNIVERSITY MEDICAL CENTER
More than half of hospitalizations due to influenza pneumonia could be prevented by influenza vaccination, according to a study led by investigators at Vanderbilt University Medical Center, published this week in the Journal of the American Medical Association.
JOURNALJAMAFUNDERNational Center for Immunization and Respiratory Diseases
Public Release: 6-Oct-2015
New test predicts teens' future risk of heart disease
UNIVERSITY OF VIRGINIA HEALTH SYSTEM
A new test can predict teenagers' future risk of heart disease, the number 1 killer of both men and women. By identifying those at risk early, the test enables doctors to encourage the healthy behaviors that could one day save the teens' lives.
JOURNALJournal of American College of Cardiology
Public Release: 6-Oct-2015
Research calls for stricter screening recommendations for family history of colon cancer
AMERICAN GASTROENTEROLOGICAL ASSOCIATION
All relatives of individuals with colorectal cancer are at increased risk for this cancer, regardless of the age of diagnosis of the index patient in the family, according to a study published online in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.
JOURNALClinical Gastroenterology and Hepatology
Public Release: 6-Oct-2015
Melatonin and mealtime: Common genetic difference could put some at greater risk of diabetes
BRIGHAM AND WOMEN'S HOSPITAL
Researchers from Brigham and Women's Hospital and the University of Murcia, Spain, have shed new light on why people who carry a common genetic mutation may be more at risk for developing type 2 diabetes. By carefully studying healthy subjects, researchers were able to chart the effect of melatonin supplements on blood sugar control. Their results, reported in Metabolism, suggest that taking melatonin close to mealtimes may put people with a common genetic variant more at risk.
JOURNALMetabolism: Clinical and ExperimentalFUNDERSpanish Government of Science and Innovation, Séneca Foundation, National Institutes of Health
Public Release: 6-Oct-2015
Jackson Laboratory researchers discover mutation involved in neurodegeneration
JACKSON LABORATORY
A mutation that increases the level of a special class of sphingolipids -- molecules important to cell structure and signaling -- can lead to neurodegeneration due to problems with neuronal membranes, reports a research team led by Jackson Laboratory Research Scientist Lihong Zhao, Ph.D. and Professor Patsy Nishina, Ph.D.
JOURNALProceedings of the National Academy of SciencesFUNDERNational Institutes of Health

Public Release: 6-Oct-2015
From molecular case studies: Genomics of exceptional responder to NOTCH inhibitor
COLD SPRING HARBOR LABORATORY
Normal T-cell development requires Notch signaling but hyperactivity can lead to cancer. Drugs that inhibit Notch, such as gamma-secretase inhibitors, are currently being tested in different cancer types but clinical remission has yet to be reported. In a paper published today in Cold Spring Harbor Molecular Case Studies, researchers describe an acute lymphoblastic leukemia patient in which GSI treatment resulted in complete remission, suggesting that GSIs may hold therapeutic promise in ALL and other cancers.
JOURNALCold Spring Harbor Molecular Case StudiesFUNDERNational Institutes of Health, Leukemia & Lymphoma Society Specialized Center of Research, William Lawrence and Blanche Hughes Foundation
Public Release: 6-Oct-2015
NIH scientists identify how normally protective immune responses kill neurons
NIH/NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
NIH scientists have discovered why certain immune responses, which typically help cells recognize and fight viral and bacterial infections, can sometimes be harmful to the brain. Many brain disorders involve the death of neurons, or nerve cells, but how these neurons die is not well understood. A new study describes how the activation of normally protective immune responses causes nerve cells to die and identifies the protein responsible, providing a potential target for therapeutic intervention.
JOURNALJournal of ImmunologyFUNDERNIH/National Institute of Allergy and Infectious Diseases
Public Release: 6-Oct-2015
New study reveals limited public understanding of dementia globally
TRINITY COLLEGE DUBLIN
Believing that dementia is a normal part of aging is the most common misconception about dementia, according to a new global study conducted by Irish researchers.
JOURNALAlzheimer's Disease and Associated Disorders
Public Release: 6-Oct-2015
Study: Burnout impacts transplant nurses
HENRY FORD HEALTH SYSTEM
More than half of nurses who work with organ transplant patients in the United States experience high levels of emotional exhaustion, a primary sign of burnout, according to a study published by researchers at Henry Ford Hospital.
JOURNALProgress in Transplantation
Public Release: 6-Oct-2015
Ceritinib in advanced lung cancer: No hint of added benefit
INSTITUTE FOR QUALITY AND EFFICIENCY IN HEALTH CARE
The drug manufacturer's dossier contained no study data suitable for an assessment for any of the two research questions.

2015-10-07 01:21

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• 浙大新规：「10万+」也能被认定为学术论文！！？

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每日生物医药科技动态汇编2015年10月7日

Public Release: 7-Oct-2015
'Chromosomal Chaos:' Complex array of mutations found in rare, aggressive leukemia
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE
Sezary syndrome, an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected. With a poor prognosis and limited options for targeted therapies,this cancer needs new treatment approaches. The team's results uncover a previously unknown, complex genomic landscape, which can be used to design new personalized drug regimens for SS patients based on their unique genetic makeup.
JOURNALNature CommunicationsFUNDERNIH/National Cancer Institute

Public Release: 7-Oct-2015
Cleaning hospital rooms with chemicals, UV rays cuts superbug transmissions
DUKE UNIVERSITY MEDICAL CENTER
In a hospital, what you can't see could hurt you. Healthcare facilities continue to battle drug-resistant organisms such as methicillin-resistant Staphylococcus aureus that loiter on surfaces even after patient rooms have been cleaned and can cause new, sometimes-deadly infections. But a new study from Duke Medicine has found that using a combination of chemicals and UV light to clean patient rooms cut transmission of four major superbugs by a cumulative 30 percent among a specific group of patients.
MEETINGIDWeek 2015FUNDERCenters for Disease Control Prevention Epicenters Program
Public Release: 7-Oct-2015
Expanding global access to radiotherapy
QUEEN'S UNIVERSITY
Queen's University researcher Timothy Hanna has co-authored a Lancet Oncology study that suggests as many as 90 per cent of people in low-income countries lack access to radiotherapy treatment.
JOURNALLancet OncologyMEETINGIC3K 2015
Public Release: 7-Oct-2015
'Psychic robot' will know what you really meant to do
UNIVERSITY OF ILLINOIS AT CHICAGO
Bioengineers at the University of Illinois at Chicago have developed a mathematical algorithm that can 'see' your intention while performing an ordinary action like reaching for a cup or driving straight up a road -- even if the action is interrupted.
JOURNALPLOS ONEFUNDERNIH/National Institute of Neurological Disorders and Stroke
Public Release: 7-Oct-2015
Two-hit therapy for breast tumors using approved drugs looks promising in animal study
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE
Disabling a cancer-causing pathway and administering an immune-molecule-based mop-up therapy eradicated a specific type of breast tumor in mice.
JOURNALCell ReportsFUNDERBreast Cancer Research Foundation, NIH/National Cancer Institute
Public Release: 7-Oct-2015
Exposure to common flame retardants may contribute to attention problems in children
COLUMBIA UNIVERSITY'S MAILMAN SCHOOL OF PUBLIC HEALTH
Prenatal exposure to some flame retardants that have been widely-used in consumer products is associated with attention problems in young children. A new study is the first to show the effects of prenatal exposure to polybrominated diphenyl ethers on children's development at ages 3, 4, and 7 years. Children with the highest exposure to certain PBDEs had approximately twice the number of maternally-reported attention problems compared to the other children in the study.
JOURNALNeurotoxicology and TeratologyFUNDERNational Institute of Environmental Health Sciences, Environmental Protection Agency, September 11th Fund of New York Community Trust and 9/11 Neediest Fund, John and Wendy Neu Family Foundation, National Philanthropic Trust
Public Release: 7-Oct-2015
Researchers need to pay attention to differences in self-control
RICE UNIVERSITY
Whether it's resisting buying a candy bar in the checkout lane or purchasing an unneeded pair of shoes on sale at the mall, self-control varies from person to person. Researchers must pay attention to these differences in individuals' self-control when assessing the impact of public policies, according to a new study by marketing and consumer behavior experts at Rice University and Vanderbilt University.
JOURNALJournal of Public Policy and Marketing
Public Release: 7-Oct-2015
Just 30 minutes a day: Regular exercise relieves asthma symptoms
CONCORDIA UNIVERSITY
Millions of people suffer from asthma. Many report having poor control of their symptoms. Fortunately, new research shows there is a simple antidote: 30 minutes of exercise a day, year-round.
JOURNALBMJ Open Respiratory ResearchFUNDERSocial Sciences and Humanities Research Council, Fonds de recherche du Quebec - Sante, Canadian Institutes of Health Research, Michel Auger Foundation of Hopital du Sacre-Coeur de Montreal

Public Release: 7-Oct-2015
New protein found in immune cells
BIOSS - CENTRE FOR BIOLOGICAL SIGNALLING STUDIES
Researchers of the University of Freiburg have discovered Kidins220/ARMS in B cells. They also determined that it plays a decisive role in the production of antibodies and the formation of B cells, which are a type of white blood cells. Various teams of researchers had already found that Kidins220/ARMS is present in nerve cells and in T cells of the immune system. However, that it is present in B cells was unknown until now.
JOURNALJournal of Experimental MedicineFUNDERGerman Research Foundation
Public Release: 7-Oct-2015
UT Southwestern researchers develop classification model for cancers caused by most frequently mutated gene in cancer
UT SOUTHWESTERN MEDICAL CENTER
UT Southwestern Medical Center researchers have developed a classification for cancers caused by KRAS, the most frequently mutated gene in cancer, that could eventually help oncologists choose more effective, customized cancer therapies.
JOURNALMolecular Cancer Research

2015-10-09 01:13

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freelane 编辑于 2015-10-09 01:39

• 多位医生被认为「不合理」用药？处罚金额上万！

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8楼

每日生物医药科技动态汇编2015年10月8日

Public Release: 8-Oct-2015
Mysterious disease may be tied to climate change, says CU Anschutz researcher
UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS
A mysterious kidney disease that has killed over 20,000 people in Central America, most of them sugar cane workers, may be caused by chronic, severe dehydration linked to global climate change, according to a new study by Richard J. Johnson, M.D., of the University of Colorado Anschutz Medical Campus.
JOURNALAmerican Journal of Kidney Diseases

Public Release: 8-Oct-2015
How small is the smallest? New record of the tiniest free-living insect provides precision
PENSOFT PUBLISHERS
The long-lasting search and debate around the size and identity of the World's smallest free-living insect seems to have now ended with the precise measurement and second record of the featherwing beetle species. Described in 1999, representatives of this minute beetle have recently been retrieved once again from fungus in Colombia. The smallest individual measured the astounding 0.325 mm. The finding made by Dr. Alexey Polilov is available in the open access journal Zookeys.
JOURNALZooKeys
Public Release: 8-Oct-2015
Study: Fracking industry wells associated with premature birth
JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH
Expectant mothers who live near active natural gas wells operated by the fracking industry in Pennsylvania are at an increased risk of giving birth prematurely and for having high-risk pregnancies, new Johns Hopkins Bloomberg School of Public Health research suggests.
JOURNALEpidemiologyFUNDERNIh/National Institute of Environmental Health Sciences, Robert Wood Johnson Foundation Heath & Society Scholars Program, National Science Foundation Integrative Graduate Education and Research Traineeship

Public Release: 8-Oct-2015
EpiPens save lives but can cut like a knife
AMERICAN COLLEGE OF EMERGENCY PHYSICIANS
Epinephrine autoinjectors can be life-saving for patients experiencing anaphylaxis -- a life-threatening emergency -- but a new case series published online Tuesday in Annals of Emergency Medicine identifies design features of EpiPens, the most commonly used autoinjector, that appear to be contributing to injuries in children ('Lacerations and Embedded Needles Caused by Epinephrine Autoinjector Use in Children').
JOURNALAnnals of Emergency Medicine
Public Release: 8-Oct-2015
Thousands of older adults and persons with disabilities transitioning home
UNIVERSITY OF CONNECTICUT
The State of Connecticut's Department of Social Services, with its state evaluator UConn's Center on Aging, successfully transitioned more than 2,200 older and disabled Connecticut residents from nursing homes and other institutions to their own home or a community setting between 2008 and 2014, as part of the federal 'Money Follows the Person Rebalancing Demonstration.'
JOURNALHealth Affairs
Public Release: 8-Oct-2015
Perceptions of fetal size influence interventions in pregnancy, BU study finds
BOSTON UNIVERSITY MEDICAL CENTER
Nearly one-third of women, without a prior cesarean, reported that they were told by their maternity care providers that their babies might be 'quite large,' leading to higher rates of medically induced labor or planned cesarean deliveries that may not be warranted, a new study co-authored by Boston University School of Public Health and Medicine researchers shows.
JOURNALMaternal and Child Health
Public Release: 8-Oct-2015
Emergency department CT scans can change physicians' diagnoses and management decisions
MASSACHUSETTS GENERAL HOSPITAL
A study from the Massachusetts General Hospital (MGH) Institute for Technology assessment finds that, after viewing CT scan results, physicians in the emergency departments of four major academic medical centers made key changes in clinical decision-making for patients with symptoms frequently seen in emergency rooms.
JOURNALRadiologyFUNDERNational Electrical Manufacturers Association
Public Release: 8-Oct-2015
Sex change hormonal treatments alter brain chemistry
ELSEVIER
Hormonal treatments administered as part of the procedures for sex reassignment have well-known and well-documented effects on the secondary sexual characteristics of the adult body, shifting a recipient's physical appearance to that of the opposite sex.
JOURNALBiological Psychiatry

Public Release: 8-Oct-2015
University of Manchester-led research shows treatment for bleeding disorder is effective
UNIVERSITY OF MANCHESTER
Researchers in Manchester have demonstrated for the first time the relative safety and effectiveness of treatment, eltrombopag, in children with persistent or chronic immune thrombocytopenia, as part of an international duo of studies.
JOURNALThe Lancet

Public Release: 8-Oct-2015
Difficulty processing speech may be an effect of dyslexia, not a cause
CARNEGIE MELLON UNIVERSITY
The cognitive skills used to learn how to ride a bike may be the key to a more accurate understanding of developmental dyslexia. And, they may lead to improved interventions. Carnegie Mellon University scientists investigated how procedural learning how individuals with dyslexia learn speech sound categories. Published in Cortex, they found that learning complex auditory categories through procedural learning is impaired in dyslexia.
JOURNALCortexFUNDERNational Institutes of Healt

Public Release: 8-Oct-2015
Difficulty processing speech may be an effect of dyslexia, not a cause
CARNEGIE MELLON UNIVERSITY
The cognitive skills used to learn how to ride a bike may be the key to a more accurate understanding of developmental dyslexia. And, they may lead to improved interventions. Carnegie Mellon University scientists investigated how procedural learning how individuals with dyslexia learn speech sound categories. Published in Cortex, they found that learning complex auditory categories through procedural learning is impaired in dyslexia.
JOURNALCortexFUNDERNational Institutes of Health
Public Release: 8-Oct-2015
Key studies from Nottingham central to major flu drug report
UNIVERSITY OF NOTTINGHAM
Flu experts from The University of Nottingham are key contributors to a new landmark report, out today, which reveals that anti-viral drugs called NAIs (like Tamiflu) have been successful in reducing deaths in flu patients in hospital. The report also reveals that preventative use of the same drugs helps fight flu infection in the home.

Public Release: 8-Oct-2015
Expanded AGS Beers Criteria offer new info, tools for safer medication use in older adults
AMERICAN GERIATRICS SOCIETY
Reflecting expert review of 6,700 studies, updates to the AGS Beers Criteria -- one of the American Geriatrics Society's most frequently cited references -- will enhance care quality as a platform for considering the risks and benefits of certain medications.
JOURNALJournal of American Geriatrics Society
Public Release: 8-Oct-2015
Protein research uncovers potential new diagnosis and therapy for breast cancer
UNIVERSITY OF YORK
Scientists at the University of York, using clinical specimens from charity Breast Cancer Now's Tissue Bank, have conducted new research into a specific sodium channel that indicates the presence of cancer cells and affects tumour growth rates.
JOURNALOncotargetFUNDERMedical Research Council

Public Release: 8-Oct-2015
A multilaminar model explains the structure of chromosomal aberrations in cancer cells
UNIVERSITAT AUTONOMA DE BARCELONA
The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers from the Universitat Autònoma de Barcelona have found that the structure of translocations in cancer cells shows that chromosomes are formed by thin plates of chromatin.
JOURNALScientific Reports
Public Release: 8-Oct-2015
New study suggests hallucinations, alone, do not predict onset of schizophrenia
UNIVERSITY OF NORTH CAROLINA HEALTH CARE
A new analysis led by researchers at the UNC School of Medicine identified 'illogical thoughts' as most predictive of schizophrenia risk. Surprisingly, perceptual disturbances -- the forerunners of hallucinations -- are not predictive.
JOURNALSchizophrenia ResearchFUNDERNIH/National Institute of Mental Health
Public Release: 8-Oct-2015
IQWiG publishes English translation of the new version of its General Methods
INSTITUTE FOR QUALITY AND EFFICIENCY IN HEALTH CARE
Changes in methods paper 4.2 primarily concern the sections on the assessment of the potential of non-drug interventions, on health economic evaluation, and on health Information.

Public Release: 8-Oct-2015
Future Oncology 10th anniversary SFI celebrates the past, present and future in cancer
FUTURE SCIENCE GROUP
Future Oncology is celebrating its tenth anniversary by publishing a Special Focus issue documenting the past, present and future of several cancers.
JOURNALFuture Oncology
Public Release: 8-Oct-2015
Breakthrough for electrode implants in the brain
LUND UNIVERSITY
For nearly nine years, researchers at Lund University have been working on developing implantable electrodes that can capture signals from single neurons in the brain over a long period of time -- without causing brain tissue damage. They are now one big step closer to reaching this goal, and the results are published in the scientific journal Frontiers in Neuroscience.
JOURNALFrontiers in Neuroscience
Public Release: 8-Oct-2015
Living in fear: Mental disorders as risk factors for chronic pain in teenagers
UNIVERSITY OF BASEL
One in four young people have experienced chronic pain and a mental disorder. According to a new report in the Journal of Pain, the onset of pain is often preceded by mental disorders: an above-average rate of incidence of depression, anxiety disorders, and behavioral disorders occurs before the onset of headaches, back pain and neck pain. The report is based on an analysis of data from 6,500 US-teenagers by researchers at the University of Basel.
h

2015-10-09 01:15

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• 关于颈动脉粥样硬化和狭窄治疗的最新指南

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9楼

每日生物医药科技动态汇编2015年10月9日

Public Release: 8-Oct-2015
Popular crime shows may help reduce sexual assault
WASHINGTON STATE UNIVERSITY
A new study reveals viewers of 'Law and Order' have a better grasp of sexual consent than viewers of other crime dramas such as 'CSI' or 'NCIS,' suggesting that individuals who watch programs in which sexual predators are punished may avoid sexual predatory behavior in real life.
JOURNALJournal of Health CommunicationPublic Release: 8-Oct-2015
A convergence of deadly signals
LUDWIG INSTITUTE FOR CANCER RESEARCH
A team of Ludwig Cancer Research scientists has mapped out how a mutant version of the epidermal growth factor receptor (EGFR) known as EGFRvIII specifically drives critical processes that alter the reading of the genome to fuel the growth of the brain cancer glioblastoma multiforme and -- most important -- how each process is linked to the other.
JOURNALMolecular CellFUNDERLudwig Cancer Research, NIH/National Institute for Neurological Diseases and Stroke, National Brain Tumor Society, Ziering Family Foundation, Ben and Catherine Ivy Foundation, UCSD Core Facility Stimulus Funding, and othersPublic Release: 8-Oct-2015
Study examines cancer-care outcomes among US hospitals
MEMORIAL SLOAN KETTERING CANCER CENTER
Efforts to rank hospitals by long-term survival rates have been hindered by the readily available administrative data derived from Medicare claims, which lacks information about cancer stage. A new MSK study published in JAMA Oncology finds that risk-adjusted Medicare claims data -- without information about the cancer stage of individual patients -- may be sufficient to calculate the long-term survival rates at hospitals providing cancer care in the US.
JOURNALJAMA Oncology

Public Release: 8-Oct-2015
Bio-inspired robotic finger looks, feels and works like the real thing
FLORIDA ATLANTIC UNIVERSITY
Most robotic parts used today are rigid, have a limited range of motion and don't really look lifelike. Inspired by nature and biology, a scientist from Florida Atlantic University has designed a novel robotic finger using shape memory alloy, a 3-D CAD model of a human finger, a 3-D printer and a unique thermal training technique. This bio-inspired robotic finger could ultimately be adapted to use as a prosthetic device, like a prosthetic hand.
JOURNALBioinspiration & Biomimetics

Public Release: 8-Oct-2015
New protein cleanup factors found to control bacterial growth
UNIVERSITY OF MASSACHUSETTS AT AMHERST
Biochemists have long known that crucial cell processes depend on a highly regulated cleanup system known as proteolysis, where specialized proteins called proteases degrade damaged or no-longer-needed proteins. They must destroy specific targets without damaging other proteins, but how this orderly destruction works is unknown in many cases. Now researchers in Peter Chien's group at UMass Amherst report finding how an essential bacterial protease controls cell growth and division.
JOURNALCellFUNDERNIH/National Institute of General Medical SciencesPublic Release: 8-Oct-2015
The father effect
MCGILL UNIVERSITY
Inheritance is not just a matter of DNA. That's what a McGill University-led team has discovered. They believe that proteins known as histones, which have attracted relatively little attention until now, may play a crucial role in the process of transmitting a father's life experiences to his offspring and could play a determining role in the health of his children and grandchildren .
JOURNALScienceFUNDERCanadian Institutes of Health Research, Genome Quebec, the Reseau de Reproduction Quebecois, Fonds de recherche Nature et technologies, Boehringer Ingelheim Fond, Swiss National Science Foundation, Novartis Research FoundationPublic Release: 8-Oct-2015
87 percent of Americans say candidates should have basic understanding of science informing public policy
RESEARCH!AMERICA
The public opinion poll of US adults commissioned by Research!America and ScienceDebate.org, conducted by Zogby Analytics, found that less than half (45 percent) of Americans say they are well-informed about the positions of the current candidates for President about public policies and public funding for science and innovation.
Public Release: 8-Oct-2015
The Lancet: Smoking set to kill one in three young men in China
THE LANCET
One in three of all the young men in China will eventually be killed by tobacco, unless a substantial proportion stop smoking, according to new research published in The Lancet.
JOURNALLancetPublic Release: 8-Oct-2015
Women and men react differently to infidelity
NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
A recent Norwegian study shows that men and women react differently to various types of infidelity. Whereas men are most jealous of sexual infidelity, so-called emotional infidelity is what makes women the most jealous. Evolutionary psychology provides an explanation for why this can be.
JOURNALPersonality and Individual DifferencesPublic Release: 8-Oct-2015
Genetic variation is key to fighting viruses
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE
Using a genome-wide association study, EPFL scientists have identified subtle genetic changes that can cause substantial differences to how we fight viral infections.
JOURNALAmerican Journal of Human GeneticsFUNDERMax Planck Society, Swiss National Science Foundation

2015-10-09 19:53

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freelane 编辑于 2015-10-10 23:16

• 狼疮、狼疮肾合并结核，高度水肿肝功能异常

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10楼

每日生物医药科技动态汇编 2015年10月9日10日

我国水产新品种研发基本情况与展望
[519] 2015/10/10
中国农科院33项成果获2014至2015年度中华农业科技奖
[344] 2015/10/10
发现青蒿素获奖对中医药意味着什么
[566] 2015/10/10
工学院陈峰课题组在微藻混合培养机制等研究中取得重要进展(图)
[330] 2015/10/10
小微藻大未来大成食品布局农畜生物科技
[577] 2015/10/10
浅谈“下一代癌症诊断市场”
[406] 2015/10/10
中玉金标记与加拿大Agronomix公司展开合作
[290] 2015/10/10
揭秘“传奇青蒿素”:如何从研发到百姓可及
[268] 2015/10/10
诺贝尔化学奖预示“纯化学”没落？
[280] 2015/10/10
国际巨头为何倾向动态DR？
[442] 2015/10/10
中国神药青蒿素的尴尬：国内药企扎堆上游利润单薄
[356] 2015/10/10
利用代谢组学解析酿酒酵母丁醇耐受机制
[372] 2015/10/10
越挤越强的枯草芽胞杆菌启动子用于蛋白质表达
[515] 2015/10/10
生物丁醇合成关键酶的新型开关机制的解析
[337] 2015/10/10
能降服CRISPR–Cas系统的anti-CRISPR蛋白
[441] 2015/10/10
龙舌兰有望从酒界进军生物燃料
[264] 2015/10/10
南通:“分布式沼气发电并网”探路前行
[375] 2015/10/10
杜邦预言:5年内,CRISPR编辑作物将会登上餐桌
[274] 2015/10/10
我国科学家实现肝单元生物3D批量打印(图)
[788] 2015/10/10
华为携手华大基因共同开发基因大数据存储系统
[835] 2015/10/09

2015-10-10 12:31

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freelane 编辑于 2015-10-17 01:06

• 你知道你想报考的学校今年热度如何吗？

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11楼

每日生物医药科技动态汇编2015年10月10日

Public Release: 10-Oct-2015
Genetic variant shown to influence women's body shape and diabetes risk
AMERICAN SOCIETY OF HUMAN GENETICS
A genetic variant near the KLF14 gene regulates hundreds of genes that govern how and where women's bodies store fat, which affects their risk of developing type 2 diabetes, according to research presented at the American Society of Human Genetics 2015 Annual Meeting in Baltimore. Specifically, different alleles, or versions, of the variant cause fat-storing cells to function differently.
MEETINGAmerican Society of Human Genetics 2015 Annual Meeting
Public Release: 10-Oct-2015
Hard-to-detect chromosomal anomalies explain neurodevelopmental birth defects
AMERICAN SOCIETY OF HUMAN GENETICS
Balanced chromosomal abnormalities (BCAs), a category of structural changes to the human genome, may account for a large portion of birth defects related to brain development and function, according to research presented at the American Society of Human Genetics 2015 Annual Meeting in Baltimore. BCAs are changes to the structure of an individual's chromosomes, in which one or more fragments of DNA breaks apart from the regions around it and is reattached elsewhere in the genome.
MEETINGAmerican Society of Human Genetics 2015 Annual Meeting
Public Release: 9-Oct-2015
Blood clotting protein triggers immune attack on the brain
GLADSTONE INSTITUTES
A new study from the Gladstone Institutes shows that a single drop of blood in the brain is sufficient to activate an autoimmune response akin to multiple sclerosis. This is the first demonstration that introduction of blood in the healthy brain is sufficient to cause peripheral immune cells to enter the brain, which then go on to cause brain damage.
JOURNALNature CommunicationsFUNDERNIH/National Institute of Neurological Disorders and Stroke, National Multiple Sclerosis Society, American Heart Association, NIH/National Heart, Blood, and Lung Institute, Pediatric Scientist Development Program, Howard Hughes Medical Institute
Public Release: 9-Oct-2015
New study provides key insights into aspirin's disease-fighting abilities
BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH
Researchers at Boyce Thompson Institute have found a new explanation for how aspirin works in the body to reduce the risk of heart disease and certain cancers. Aspirin's active form, salicylic acid, blocks a protein called HMGB1, which triggers inflammation in damaged tissues. The new findings may explain the disease-preventing effects of a low-dose aspirin regimen and offer hope that more effective aspirin-like drugs may be developed for a wide variety of diseases.
JOURNALMolecular MedicineFUNDERNational Science Foundation, National Institutes of Health, Triad Foundation, Associazione Italiana Ricerca sul Cancro
Public Release: 9-Oct-2015
Scripps experts present at 2015 TCT scientific symposium
SCRIPPS HEALTH
From new methods for preventing stroke, to non-surgical treatment of heart valve defects and learning from complicated cases, Scripps Health cardiology experts will share leading edge techniques for improving heart care during the 27th Transcatheter Cardiovascular Therapeutics.
MEETINGTranscatheter Cardiovascular Therapeutics
Public Release: 9-Oct-2015
Nurses could help cut smoking rates in China, according to UCLA-led study
UNIVERSITY OF CALIFORNIA - LOS ANGELES
China has a big smoking problem. Three-hundred fifty million smoke and one million a year die from smoking related causes. In a two-part study, published online in the Journal of Advanced Nursing, an international team of investigators found that nurses can play a pivotal role in helping smokers to quit. But in order to do so, they need knowledge and skills.
JOURNALJournal of Advanced Nursing

Public Release: 9-Oct-2015
A better way to read the genome
UNIVERSITY OF CONNECTICUT
UConn genomicists have sequenced the RNA of the most complicated gene known in nature, using a hand-held sequencer no bigger than a cell phone. The researchers teamed up with Oxford Nanopore Technologies to show that the company's MinION nanopore sequencer can sequence genes faster, better, and at a much lower cost than the standard technology. Brenton Graveley will discuss the research at the Oxford Nanopore MinION Community Meeting at New York Genome Center Dec. 3.
JOURNALGenome BiologyFUNDERNational Institutes of Health

Public Release: 9-Oct-2015
UV light robots cut c. diff transmissions by 25 percent on cancer patient floors
UNIVERSITY OF PENNSYLVANIA SCHOOL OF MEDICINE
New research from Penn Medicine infection control specialists found that ultraviolet robots helped reduce the rates transmission of the common bacterial infection known as Clostridium difficile among cancer inpatients -- mostly blood cancer patients, a group more vulnerable to hospital-acquired infections -- by 25 percent. The interventions also saved about $150,000 in annual direct medical costs.
MEETINGIDWeek 2015
Public Release: 9-Oct-2015
Antiviral compound provides full protection from Ebola virus in nonhuman primates
US ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES
Rhesus monkeys were completely protected from the deadly Ebola virus when treated three days after infection with a compound that blocks the virus's ability to replicate. These encouraging preclinical results suggest the compound, known as GS-5734, should be further developed as a potential treatment, according to research findings to be presented tomorrow at the IDWeek conference.
MEETINGIDWeek 2015FUNDERDefense Threat Reduction Agency, Medical Countermeasure Systems Joint Project Management Office, US Department of Defense
Public Release: 9-Oct-2015
Moffitt researchers develop novel theoretical approach to reduce antibiotic resistance
H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE
Moffitt Cancer Center researchers have developed a novel mathematical method inspired by Darwinian evolution to use current antibiotics to eliminate or reduce the development of antibiotic-resistant bacteria.
JOURNALPLOS Computational BiologyFUNDEREngineering and Physical Sciences Research Council, National Institutes of Health Loan Repayment Program, National Cancer Institute Integrative Cancer Biology Program, National Cancer Institute Physical Sciences in Oncology Centers

2015-10-10 23:11

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• 开学了，分享一些华西考博的心得

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freelane

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12楼

每日生物医药科技动态汇编2015年10月11日
我国水产新品种研发基本情况与展望
中国农科院33项成果获2014至2015年度中华农业科技奖
发现青蒿素获奖对中医药意味着什么
工学院陈峰课题组在微藻混合培养机制等研究中取得重要进展(图)
小微藻大未来大成食品布局农畜生物科技
浅谈“下一代癌症诊断市场”
中玉金标记与加拿大Agronomix公司展开合作
揭秘“传奇青蒿素”:如何从研发到百姓可及
诺贝尔化学奖预示“纯化学”没落？
国际巨头为何倾向动态DR？
中国神药青蒿素的尴尬：国内药企扎堆上游利润单薄
利用代谢组学解析酿酒酵母丁醇耐受机制
越挤越强的枯草芽胞杆菌启动子用于蛋白质表达
生物丁醇合成关键酶的新型开关机制的解析
能降服CRISPR–Cas系统的anti-CRISPR蛋白
龙舌兰有望从酒界进军生物燃料
南通:“分布式沼气发电并网”探路前行
杜邦预言:5年内,CRISPR编辑作物将会登上餐桌
我国科学家实现肝单元生物3D批量打印(图)
Biogen And Four Other Biotech Stocks Worth Watching
Forbes
Saturday, October 10, 2015 - 9:12am
tags:
Biogen, Esperion, Zafgen, Clovis Oncology, Portola
One man, an army of contractors and a half-billion-dollar deal with Genentech's parent
Bizjournals.com
Saturday, October 10, 2015 - 9:10am
tags:
Genentech, Roche
Boston Scientific mesh verdict slashed to $10 million
Mass Device
Saturday, October 10, 2015 - 9:09am
tags:
devices, Boston Scientific, pelvic mesh
4 Things Johnson & Johnson Should Address When it Reports Its Q3 Results
Motley Fool
Saturday, October 10, 2015 - 9:09am
tags:
JNJ, earnings, Invokana, daratumumab, devices
Lilly buys rights to intranasal diabetes treatment
Marketwatch
Saturday, October 10, 2015 - 9:08am
tags:
Eli Lilly, diabetes, Locemia Solutions
Biogen's Commercial Head Exits as Drugmaker Reshuffles Sales
Bloomberg
Friday, October 9, 2015 - 3:58pm
tags:
Biogen, reorganization
Why Cholesterol and Alzheimer’s Could Drive Eli Lilly Shares Much Higher
24/7 Wall St
Friday, October 9, 2015 - 3:56pm
tags:
Eli Lilly, solanezumab, evacetrapib, Alzheimer's disease
Pfizer turns aside yet another case alleging Zoloft caused birth defects
Fierce Pharma
Friday, October 9, 2015 - 3:54pm
tags:
Pfizer, Zoloft, antidepressants, birth defects
Wyeth, Cordis bury the hatchet in stent patent spat with Abbott, Boston Scientific
Mass Device
Friday, October 9, 2015 - 11:52am
tags:
Wyeth, Pfizer, Cordis, Abbott Labs, JNJ, Boston Scientific, devices, drug-eluting stents, patents, Xience
This Double-Whammy Sent Merck Shares Notably Lower in September
Motley Fool
Friday, October 9, 2015 - 11:19am
tags:
Merck, Jardiance, Januvia, Keytruda
Allergan, Valeant rethink 'acquire-and-hike' pricing strategy amid Shkreli-driven anger
BioPharma Dive
Friday, October 9, 2015 - 11:04am
tags:
Allergan, Valeant Pharmaceuticals, drug pricing, Martin Shkreli

2015-10-11 17:57

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freelane 编辑于 2015-10-11 23:24

• 重磅！！心理咨询师证被取消！人社部公布 140 项国家职业资格目录!

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13楼

每日生物医药科技动态汇编2015年10月12日

未来医学：虚拟医疗展示动态身体部位助医生诊疗
[225] 2015/10/12
家用医疗器械迎来发展期消费+需求驱动370+亿元市场规模
[308] 2015/10/12
7000亿也不够分数字化医疗服务需要更多新模式
[363] 2015/10/12
健康医药借“互联网+”冲刺千亿产值
[342] 2015/10/12
肿瘤“液态活检”可能是基因测序市场的下一个爆发点
[221] 2015/10/12
TPP协议敲定，对生物制药行业的5大影响
[342] 2015/10/12
“千人计划”专家打造我国首个“药物种子库”，实现化合物库从0到10亿个种类的突破
[191] 2015/10/12
修正药业拟在香港IPO 募资117亿港币
[317] 2015/10/12
有潜力的肿瘤治疗新方法概述
[182] 2015/10/12
60%在研结直肠癌药物为靶向药物
[165] 2015/10/12
专家建议：建立独立垂直中医药管理体制
[185] 2015/10/12
医院拿什么开展精准医疗？
[319] 2015/10/12
叶酸：心血管疾病的“天敌”
[165] 2015/10/12
蒿甲醚针剂：将青蒿素带到疟疾病人身边
[150] 2015/10/12
礼来和信达生物拓展战略联盟(图)
[446] 2015/10/12

2015-10-14 00:22

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freelane 编辑于 2015-10-14 00:25

• 医生实行考核制了，考核不合格开除！！！

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freelane

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14楼

每日生物医药科技动态汇编2015年10月13日

Public Release: 13-Oct-2015
Four in 10 older adults burdened by demands of health-care system
JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH
Nearly four in 10 older adults say that managing their health care needs is difficult for them or their families, that medical appointments or tests get delayed or don't get done, or that all of the requirements of their health care are too much to handle, new Johns Hopkins Bloomberg School of Public Health research suggests.
JOURNALJournal of General Internal MedicineFUNDERNIH/National Institute of Mental Health, NIH/National Institute on Aging, AFAR, John A. Hartford Foundation, Atlantic Philanthropies, Starr Foundation, and others
Public Release: 13-Oct-2015
Drug-resistant E. coli bacteria increasingly found in community hospitals
SOCIETY FOR HEALTHCARE EPIDEMIOLOGY OF AMERICA
The number of infections caused by highly antibiotic-resistant extended-spectrum beta-lactamase-producing Escherichia coli (E. coli) bacteria is increasing in community hospitals, a setting in which most Americans receive care, according to a new study published online today in Infection Control & Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.
JOURNALInfection Control and Hospital Epidemiology
Public Release: 13-Oct-2015
Preclinical study shows potential to increase the effectiveness of leukemia treatments
VIRGINIA COMMONWEALTH UNIVERSITY
Preclinical experiments led by a team of researchers at VCU Massey Cancer Center have shown that blocking the production of a protein known as chromodomain helicase DNA-binding protein 4 may help increase the effectiveness of first-line treatments for acute myeloid leukemia, a particularly lethal blood cancer that is increasing in incidence among older adults.
JOURNALBloodFUNDERLeukemia and Lymphoma Society of America, National Institutes of Health, NIH/National Cancer Institute
Public Release: 13-Oct-2015
Obstructive sleep apnea associated with incident heart failure, death in women
BRIGHAM AND WOMEN'S HOSPITAL
Results of research, published in Circulation in October, found that sex-specific differences exist in the relationship between OSA and CV disease and that, in women, sleep apnea was associated with higher blood levels of troponin (hs-TnT), a marker that provides information on early evidence of heart injury.
JOURNALCirculationFUNDERNIH/National Heart, Lung, and Blood Institute, American Heart Association
Public Release: 13-Oct-2015
Sitting for long periods not bad for health
UNIVERSITY OF EXETER
New research from the University of Exeter and University College London has challenged claims that sitting for long periods increases the risk of an early death even if you are otherwise physically active.
JOURNALInternational Journal of EpidemiologyFUNDERMedical Research Council, British Heart Foundation, Stroke Association, NIH/National Heart, Lung and Blood Institute, NIH/National Institute on Aging

Public Release: 13-Oct-2015
New field of application for versatile helper
TECHNICAL UNIVERSITY OF MUNICH (TUM)
In Alzheimer's disease proteins clump together to long fibrils causing the death of nerve cells. Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum Muenchen have now uncovered how the protein interacts with other proteins.
JOURNALNature Structural & Molecular BiologyFUNDERHelmholtz Zentrum Muenchen, DFG
Public Release: 13-Oct-2015
Non-lethal firearm related hospitalizations in USA cost $679 million annually
COMPUSCRIPT LTD
A retrospective study reveals the cost of inpatient hospitalizations caused by non-lethal firearm-related injuries (FRIs) and gun violence in the USA at $679 million annually. The authors also found that FRIs disproportionately affects the young (18- to 24-year-olds), poor and minority males (Hispanics and Blacks) in urban settings. A clear urban/rural divide was noted as well as geographical variations, with the western USA having the highest odds of hospitalization caused by a FRI.
JOURNALFamily Medicine and Community Health
Public Release: 13-Oct-2015
Possible new treatment for neurodegenerative diseases found
UNIVERSITY OF LIVERPOOL
Researchers at the University of Liverpool have found that a well-established anti-epileptic drug could also be used as a treatment for neurodegenerative diseases.
JOURNALMolecular Neurodegeneration
Public Release: 13-Oct-2015
New study has important implications for the design of a protective HIV vaccine
UNIVERSITY OF THE WITWATERSRAND
A Ph.D. student from Wits University published a study describing how the changing viral swarm in an HIV infected person can drive the generation of antibodies able to neutralize HIV strains from across the world. The study has important implications for the design of a protective HIV vaccine.
JOURNALNature Medicine
Public Release: 13-Oct-2015
Greater neighborhood access to fast-food outlets linked to lower bone mass in infants
INTERNATIONAL OSTEOPOROSIS FOUNDATION
New research from the MRC Lifecourse Epidemiology Unit at the University of Southampton in the UK indicates that neighborhood exposure to fast-food outlets is potentially linked to poorer bone development in early childhood.
JOURNALOsteoporosis International

2015-10-14 00:25

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• 公立医院动态编制来了！打破铁饭碗，干不好走人

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freelane

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15楼

医药生命科学动态跟踪 ddddddddddd

2015-10-16 00:46

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freelane 编辑于 2015-10-16 00:50

• 协和、北大、中山医考博体会（2年的努力，终成正果）

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16楼

每日生物医药科技动态汇编2015年10月15日

Public Release: 15-Oct-2015
New consensus statements target controversial trial results on intracranial pressure monitoring in severe traumatic brain injury
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS
Seven consensus statements developed by 23 international opinion leaders in the acute care of patients with severe traumatic brain injury (sTBI) provide a clear interpretation of clinical trial results that compared intracranial pressure (ICP)-based management to a treatment protocol guided by CT-imaging and examination without ICP monitoring. Results of the BEST TRIP trial led to ongoing debate over the value of ICP monitoring in sTBI. These new consensus statements, which will help guide practicing physicians and researchers, are published in Journal of Neurotrauma.
JOURNALJournal of Neurotrauma

Public Release: 15-Oct-2015
Team describes rapid, sensitive test for HIV mutations
BROWN UNIVERSITY
Brown University researchers have developed a method for detecting single nucleotide mutations directly in the RNA of HIV, including mutations that make it resistant to some drugs. In lab tests, the single-step system performed more quickly and with better sensitivity than standard technologies.
JOURNALJournal of Molecular DiagnosticsFUNDERNIH/National Institute of Allergy and Infectious Diseases, Lifespan/Tufts/Brown CFAR, Brown University
Public Release: 15-Oct-2015
Sexual transmission of Ebola virus in Liberia confirmed using genomic analysis
US ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES
A suspected case of sexual transmission of Ebola virus disease in Liberia was confirmed using genomic analysis, thanks to in-country laboratory capabilities established by US Army scientists in collaboration with the Liberian Institute for Biomedical Research. The work, described in today's edition of the New England Journal of Medicine, provides molecular evidence of Ebola virus transmission between a disease survivor and his female partner. It also demonstrates the value of real-time genomic surveillance during an outbreak.
JOURNALNew England Journal of MedicineFUNDERDefense Threat Reduction Agency, Global Biosurveillance Technology Initiative, Global Emerging Infections Surveillance, Illumina, NIH/National Institute of Allergy and Infectious Diseases, National Institutes of Health
Public Release: 15-Oct-2015
Is the first commercial gene therapy product within sight?
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS
Highly anticipated phase III clinical trial results of Spark Therapeutics's gene therapy to treat visual impairment are due by year-end and could have profound implications for the broader gene therapy field, leading to the first approved product in the US. A detailed analysis of the design and use of SPK-RPE65 to treat Leber congenital amaurosis type 2 (LCA2), the possibility of expanding its use to other patient populations, and the anticipated impact of a first commercial gene therapy product.
JOURNALHuman Gene Therapy

Public Release: 15-Oct-2015
Sendai virus defends against a threat
HIROSHIMA UNIVERSITY
A research group at Hiroshima University, Japan demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. They examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal transduction pathway of interferon gamma. Researchers are now trying to screen low molecular weight compounds for developing new anti-viral drugs.
JOURNALJournal of VirologyFUNDERInamori Foundation, Glaxo-SmithKline Japan, Takeda Science Foundation, Japan Society for the Promotion of Science
Public Release: 15-Oct-2015
Study reveals why cancer anemia treatment leads to tumor growth
UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER
Scientists have shown why a drug widely used to treat chemotherapy-induced anemia in ovarian and breast cancer patients also may shorten survival times in some patients by inadvertently stimulating tumor growth.
JOURNALCancer Cell

Public Release: 15-Oct-2015
The shape of a pipe dramatically affects how pollutants will spread
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
The shape of a pipe has a large effect on the spreading of particles suspended in the fluid flowing through the pipe. Calculations show that round pipes produce symmetrical spreading along the flow direction, whereas rectangular pipes give an asymmetry.
JOURNALPhysical Review LettersFUNDERNational Science Foundation

Public Release: 15-Oct-2015
Laser-based imaging tool could increase accuracy, safety of brain tumor surgery
UNIVERSITY OF MICHIGAN HEALTH SYSTEM
U-M Health System researchers are testing technology that gives brain surgeons real-time microscopic vision of tumors. 'It allows the surgical decision-making process to become data driven instead of relying on the surgeon's best guess,' said Daniel Orringer, M.D., the U-M neurosurgeon piloting the technology with a team of physicians and medical school students.
JOURNALScience Translational MedicineFUNDERNIH/National Institute of Biomedical Imaging and Bioengineering, NIH/National Cancer Institute, NIH/National Institute of Neurologic Disorders and Stroke, National Institute of Health, and others

Public Release: 15-Oct-2015
Mini DNA sequencer tests true
EUROPEAN MOLECULAR BIOLOGY LABORATORY - EUROPEAN BIOINFORMATICS INSTITUTE
The MinION, a handheld DNA-sequencing device developed by Oxford Nanopore, has been tested and evaluated by an independent, international consortium coordinated by EMBL's European Bioinformatics Institute. The innovative device opens up new possibilities for using sequencing technology in the field, for example in tracking disease outbreaks, testing packaged food or the trafficking of protected species.
JOURNALF1000ResearchFUNDERWellcome Trust, Rosetrees Trust, Biotechnology and Biological Sciences Research Council, Canadian Institutes of Health Research, National Science Foundation, National Institutes of Health, NIH/National Human Genome Research Institute, and others
Public Release: 15-Oct-2015
Journal Resuscitation publishes updated European Resuscitation Council guidelines
ELSEVIER
Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced the publication of the 2015 European Resuscitation Council guidelines, in the latest issue of journal Resuscitation. These guidelines are based on an extensive international review of all the science supporting cardiopulmonary resuscitation (CPR). The 2015 International Consensus on CPR Science, is also published in Resuscitation today. This year also marks the 55th anniversary since CPR was first developed.
JOURNALResuscitation

2015-10-16 00:46

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• 成人股骨头坏死临床诊疗指南(2016)

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17楼

每日生物医药科技动态汇编2015年10月16日

Public Release: 16-Oct-2015
Wayne State scientists make advancements that may lead to new treatments for Parkinson's
WAYNE STATE UNIVERSITY - OFFICE OF THE VICE PRESIDENT FOR RESEARCH
A research team led by Assia Shisheva, Ph.D., professor of physiology in Wayne State University's School of Medicine, has made breakthrough advancements on a new molecular mechanism that may provide a means to 'melt' pathological clumps known as Lewy bodies in certain areas of the brain. These clumps are a hallmark sign of Parkinson's disease.
JOURNALJournal of Biological ChemistryFUNDERNIH/National Institute of Diabetes, Digestive and Kidney Disease, Wayne State University, American Diabetes Association
Public Release: 16-Oct-2015
How reward and daytime sleep boost learning
ELIFE
Rewarding learning selectively enhances the consolidation of learned information during sleep. This human study builds on what we know from Drosophila by showing how sleep and reward combine to boost memory.
JOURNALeLife
Public Release: 16-Oct-2015
Huntington's disease protein controls movement of precious cargo inside cells, study finds
UNIVERSITY AT BUFFALO
We know that the Huntingtin protein is responsible for Huntington's disease. Create the protein in the wrong form in the human body, and symptoms develop. But why this happens is unknown. A new University at Buffalo study moves toward understanding this enigma. The research, published in Human Molecular Genetics, shows that Htt controls the movement of precious cargo traveling up and down neurons, the cells that form the core of the nervous system in animals.
JOURNALHuman Molecular GeneticsFUNDERNIH/National Institute of Neurological Disorders and Stroke, John R. Oishei Foundation
Public Release: 16-Oct-2015
College students say prescription stimulants easy to find on campus
OHIO STATE UNIVERSITY
Seven out of 10 college students say it is somewhat or very easy to obtain controlled stimulants without a prescription, according to a new survey conducted on eight US campuses.

Public Release: 16-Oct-2015
What can we learn from nutrigenomics testing?
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS
There is insufficient scientific evidence to support the utility of commercially available nutrigenomics tests that claim to link genetic variants to dietary intake or nutrition-related disorders. While nutrigenomics remains a promising tool for advancing personalized medicine and healthcare, more research is needed before it can help guide health-related decisions, according to a study published in OMICS: A Journal of Integrative Biology.
JOURNALOMICS: A Journal of Integrative Biology
Public Release: 16-Oct-2015
Temple finds app facilitates early detection and treatment of COPD exacerbation symptoms
TEMPLE UNIVERSITY HEALTH SYSTEM
A digital health application for reporting symptoms of chronic obstructive pulmonary disease (COPD) facilitated early detection and treatment of COPD exacerbation symptoms, according to an analysis from the Temple Lung Center published by Telemedicine and eHealth.
JOURNALTelemedicine and e-Health

Public Release: 16-Oct-2015
Nicotine gives brain more codeine relief, risk of addiction
UNIVERSITY OF TORONTO
According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer -- which could put them at a higher risk for addiction, and possibly even overdose. These findings are part a new way of seeing the brain's role when it comes to drugs and toxins.
JOURNALNeuropsychopharmacology

Public Release: 16-Oct-2015
Maternal influences
UNIVERSITY OF VETERINARY MEDICINE -- VIENNA
In horse breeding, stallions are usually used to establish a breeding line. In some cases, however, the maternal lineage plays a more important role. Researchers from the Vetmeduni Vienna looked at the gestation length of different mare families and discovered that the length of gestation varies significantly from lineage to lineage. Certain families also produce more female offspring than male foals. The results were published in the journal PLOS ONE.
JOURNALPLOS ONE

Public Release: 16-Oct-2015
The CNIO discovers a link between a rare form of anemia and cancer
CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO)
More than 20 percent of people affected by Diamond-Blackfan anemia, a rare disease, develop various types of tumors throughout their lives. CNIO researchers have created the first animal model with this type of anemia that also recapitulates the predisposition to cancer. The finding, published in the journal Cell Reports, could potentially improve current treatments for this type of anemia, which, to date, are only effective in resolving the hematological disorders.
JOURNALCell Reports

Public Release: 16-Oct-2015
Scent is the route to the very best fruit
LINKÖPING UNIVERSITY
Monkeys and other primates have a better sense of smell than is often claimed. Researchers at Linköping University and two German universities have studied spider monkeys -- and found that they are experts at sniffing out optimally ripe fruit.
JOURNALScientific Reports

2015-10-16 23:52

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freelane 编辑于 2015-10-17 01:11

• 你知道你想报考的学校今年热度如何吗？

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每日生物医药科技动态汇编2015年10月17日

Public Release: 17-Oct-2015
Childhood infections associated with increased risk of early heart attack
EUROPEAN SOCIETY OF CARDIOLOGY
Infections in childhood are associated with an increased risk of early heart attacks, according to research presented today at Acute Cardiovascular Care 2015 by Dr. Andriany Qanitha, a Ph.D. candidate at the Academic Medical Centre in Amsterdam, the Netherlands. Unhealthy lifestyles in adulthood appear to compound the risk of early heart attack.
MEETINGAcute Cardiovascular Care 2015
Public Release: 17-Oct-2015
Pacemakers identify atrial fibrillation and enable initiation of stroke prevention
EUROPEAN SOCIETY OF CARDIOLOGY
Pacemakers identify atrial fibrillation and enable initiation of anticoagulation to prevent strokes, according to research presented today at Acute Cardiovascular Care 2015 by Dr. Nathan Denham, a cardiologist at Warrington Hospital, UK.
MEETINGAcute Cardiovascular Care 2015
Public Release: 17-Oct-2015
Sniffing and gasping can prevent fainting
EUROPEAN SOCIETY OF CARDIOLOGY
Sniffing and gasping can prevent fainting, reveals research presented today at Acute Cardiovascular Care 2015 by Dr Marta Bavolarova, a cardiologist at Louis Pasteur University Hospital in Kosice, Slovak Republic.
MEETINGAcute Cardiovascular Care 2015
Public Release: 17-Oct-2015
Study finds mechanisms of early insulin treatment for diabetes may produce better outcomes
AMERICAN OSTEOPATHIC ASSOCIATION
A pilot study of 23 adults with newly diagnosed type 2 diabetes found early insulin therapy to be as effective as 15 months of oral therapy and may improve the body's ability to produce insulin.
MEETINGOMED 2015
Public Release: 16-Oct-2015
Discovery opens door to new strategy for cancer immunotherapy
DANA-FARBER CANCER INSTITUTE
New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.
JOURNALScienceFUNDERLeRoy Schecter Research Foundation, National Institutes of Health, Arthritis National Research Foundation

Public Release: 16-Oct-2015
Nuclear transport problems linked to ALS and FTD
NIH/NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Three teams of scientists supported by the showed that a genetic mutation linked to some forms of ALS and FTD may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center. The results provide a possible strategy for treating the two diseases.
JOURNALNatureFUNDERNational Institutes of Health, Robert Packard Center for ALS Research at Johns Hopkins University, Muscular Dystrophy Association, Alzheimer's Drug Discovery Foundation, Judith and Jean Pape Adams Charitable Foundation
Public Release: 16-Oct-2015
Nanodiamonds might prevent tooth loss after root canals
UNIVERSITY OF CALIFORNIA - LOS ANGELES
Nanodiamonds may help patients that have had the dreaded root canal. UCLA dental researchers have developed a nanodiamond-reinforced version of gutta percha, the compound that is used to fill void spaces in dental root canals to prevent infection that can lead to tooth loss. Tested in patient-extracted teeth, the nanodiamond-embedded polymer was substantially stronger than conventional gutta percha. In addition, the scientists tested gutta percha with nanodiamonds that had been loaded with antibiotics and found that the compound effectively prevented bacterial infection.
JOURNALACS Nano
Public Release: 16-Oct-2015
Protein found in malaria could help stop cancer
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.
JOURNALCancer Cell
Public Release: 16-Oct-2015
New Jersey researchers use neuroimaging to explore reading deficits after left stroke
KESSLER FOUNDATION
Researchers at Kessler Foundation and Rutgers University correlated neuroimaging data with reading deficits in patients with subacute left hemispheric stroke. Findings add to knowledge of neural mechanisms of reading and may be useful in developing reading interventions that address specific neurological deficits. 'Neurally dissociable cognitive components of reading deficits in subacute stroke', published in Frontiers in Human Neuroscience, was authored by O. Boukrina, PhD, et al. Few studies have focused on cognitive components of reading.
JOURNALFrontiers in Human NeuroscienceFUNDERNIH/National Institute of Child Health & Human Development, Mabel H. Flory Foundation

Public Release: 16-Oct-2015
Investigators create complex kidney structures from human stem cells derived from adults
BRIGHAM AND WOMEN'S HOSPITAL
Investigators at Brigham and Women's Hospital and the Harvard Stem Cell Institute have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients. The kidney structures formed could be used to study abnormalities of kidney development, chronic kidney disease, the effects of toxic drugs, and be incorporated into bioengineered devices to treat patients with acute and chronic kidney injury.
JOURNALNature BiotechnologyFUNDERNational Institutes of Health, Grant-in-Aid for Japan Society for the Promotion of Science, Postdoctoral Fellowship for Research Abroad, American Heart Association
Public Release: 17-Oct-2015
Childhood infections associated with increased risk of early heart attack
EUROPEAN SOCIETY OF CARDIOLOGY
Infections in childhood are associated with an increased risk of early heart attacks, according to research presented today at Acute Cardiovascular Care 2015 by Dr. Andriany Qanitha, a Ph.D. candidate at the Academic Medical Centre in Amsterdam, the Netherlands. Unhealthy lifestyles in adulthood appear to compound the risk of early heart attack.
MEETINGAcute Cardiovascular Care 2015Public Release: 17-Oct-2015
Pacemakers identify atrial fibrillation and enable initiation of stroke prevention
EUROPEAN SOCIETY OF CARDIOLOGY
Pacemakers identify atrial fibrillation and enable initiation of anticoagulation to prevent strokes, according to research presented today at Acute Cardiovascular Care 2015 by Dr. Nathan Denham, a cardiologist at Warrington Hospital, UK.
MEETINGAcute Cardiovascular Care 2015Public Release: 17-Oct-2015
Study finds mechanisms of early insulin treatment for diabetes may produce better outcomes
AMERICAN OSTEOPATHIC ASSOCIATION
A pilot study of 23 adults with newly diagnosed type 2 diabetes found early insulin therapy to be as effective as 15 months of oral therapy and may improve the body's ability to produce insulin.
MEETINGOMED 2015Public Release: 16-Oct-2015
Discovery opens door to new strategy for cancer immunotherapy
DANA-FARBER CANCER INSTITUTE
New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.
JOURNALScienceFUNDERLeRoy Schecter Research Foundation, National Institutes of Health, Arthritis National Research Foundation

Public Release: 16-Oct-2015
Nuclear transport problems linked to ALS and FTD
NIH/NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
Three teams of scientists supported by the showed that a genetic mutation linked to some forms of ALS and FTD may destroy neurons by disrupting the movement of materials in and out of the cell's nucleus, or command center. The results provide a possible strategy for treating the two diseases.
JOURNALNatureFUNDERNational Institutes of Health, Robert Packard Center for ALS Research at Johns Hopkins University, Muscular Dystrophy Association, Alzheimer's Drug Discovery Foundation, Judith and Jean Pape Adams Charitable FoundationPublic Release: 16-Oct-2015
Nanodiamonds might prevent tooth loss after root canals
UNIVERSITY OF CALIFORNIA - LOS ANGELES
Nanodiamonds may help patients that have had the dreaded root canal. UCLA dental researchers have developed a nanodiamond-reinforced version of gutta percha, the compound that is used to fill void spaces in dental root canals to prevent infection that can lead to tooth loss. Tested in patient-extracted teeth, the nanodiamond-embedded polymer was substantially stronger than conventional gutta percha. In addition, the scientists tested gutta percha with nanodiamonds that had been loaded with antibiotics and found that the compound effectively prevented bacterial infection.
JOURNALACS NanoPublic Release: 16-Oct-2015
Protein found in malaria could help stop cancer
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE
Researchers at the Translational Genomics Research Institute joined an international team of scientists in discovering how a protein from malaria could some day help stop cancer.
JOURNALCancer CellPublic Release: 16-Oct-2015
New Jersey researchers use neuroimaging to explore reading deficits after left stroke
KESSLER FOUNDATION
Researchers at Kessler Foundation and Rutgers University correlated neuroimaging data with reading deficits in patients with subacute left hemispheric stroke. Findings add to knowledge of neural mechanisms of reading and may be useful in developing reading interventions that address specific neurological deficits. 'Neurally dissociable cognitive components of reading deficits in subacute stroke', published in Frontiers in Human Neuroscience, was authored by O. Boukrina, PhD, et al. Few studies have focused on cognitive components of reading.
JOURNALFrontiers in Human NeuroscienceFUNDERNIH/National Institute of Child Health & Human Development, Mabel H. Flory Foundation

1
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2015-10-17 01:12

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freelane 编辑于 2015-10-18 00:20

• 上海交通大学医学院“青年千人”吴学锋课题组诚聘博士后/研究助理/技术员

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2015-10-18 00:20

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freelane 编辑于 2015-10-18 17:24

• 多位医生被认为「不合理」用药？处罚金额上万！

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freelane

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20楼

每日生物医药科技动态汇编2015年10月19日
Public Release: 18-Oct-2015
Premature birth appears to weaken brain connections
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
Babies born prematurely face an increased risk of neurological and psychiatric problems that may be due to weakened connections in brain networks linked to attention, communication and the processing of emotions, according to new research at Washington University School of Medicine in St. Louis.
MEETINGNeuroscience 2015FUNDERNIH/National Institute of Mental Health, NIH/National Institute of Neurological Disorders and Stroke, NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health
Public Release: 18-Oct-2015
For lung cancer patients, IMRT associated with lesser side effects, better tolerance of chemotherapy, compared to conventional radiation therapy
UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER
An analysis of an international, cooperative-led trial of patients with locally advanced non-small cell lung cancer has shown that those who received intensity modulated radiation therapy had less severe lung toxicity and were able to better tolerate their chemotherapy, compared to patients who received 3-D conformal radiation therapy.
MEETINGAmerican Society for Radiation Oncology's 57th Annual Meeting
Public Release: 18-Oct-2015
Researchers close in on a blood test for Alzheimer's disease
AMERICAN OSTEOPATHIC ASSOCIATION
Researchers from the Rowan University School of Osteopathic Medicine are nearing development of a blood test that can accurately detect the presence of Alzheimer's disease, which would give physicians an opportunity to intervene at the earliest, most treatable stage.
MEETINGOMED 2015
Public Release: 17-Oct-2015
New research offers first clinical evidence on the mental health toll of human trafficking
KING'S COLLEGE LONDON
A new study by researchers from the Institute of Psychiatry, Psychology & Neuroscience at King's College London provides the first clinical evidence on the toll human trafficking has on mental health, including high levels of post-traumatic stress disorder and depression, amongst a patient population in South London.
JOURNALLancet Psychiatry
Public Release: 17-Oct-2015
Childhood infections associated with increased risk of early heart attack
EUROPEAN SOCIETY OF CARDIOLOGY
Infections in childhood are associated with an increased risk of early heart attacks, according to research presented today at Acute Cardiovascular Care 2015 by Dr. Andriany Qanitha, a Ph.D. candidate at the Academic Medical Centre in Amsterdam, the Netherlands. Unhealthy lifestyles in adulthood appear to compound the risk of early heart attack.
MEETINGAcute Cardiovascular Care 2015
Public Release: 17-Oct-2015
Pacemakers identify atrial fibrillation and enable initiation of stroke prevention
EUROPEAN SOCIETY OF CARDIOLOGY
Pacemakers identify atrial fibrillation and enable initiation of anticoagulation to prevent strokes, according to research presented today at Acute Cardiovascular Care 2015 by Dr. Nathan Denham, a cardiologist at Warrington Hospital, UK.
MEETINGAcute Cardiovascular Care 2015
Public Release: 17-Oct-2015
Sniffing and gasping can prevent fainting
EUROPEAN SOCIETY OF CARDIOLOGY
Sniffing and gasping can prevent fainting, reveals research presented today at Acute Cardiovascular Care 2015 by Dr Marta Bavolarova, a cardiologist at Louis Pasteur University Hospital in Kosice, Slovak Republic.
MEETINGAcute Cardiovascular Care 2015
Public Release: 17-Oct-2015
Cancer drug improved cognition and motor skills in small Parkinson's clinical trial
GEORGETOWN UNIVERSITY MEDICAL CENTER
An FDA-approved drug for leukemia improved cognition, motor skills and non-motor function in patients with Parkinson's disease and Lewy body dementia in a small phase I clinical trial, report researchers at Georgetown University Medical Center in Washington. In addition, the drug, nilotinib (Tasigna by Novartis), led to statistically significant and encouraging changes in toxic proteins linked to disease progression (biomarkers).
MEETINGNeuroscience 2015FUNDERGeorgetown-Howard Universities Center for Clinical and Translational Science
Public Release: 17-Oct-2015
Study finds mechanisms of early insulin treatment for diabetes may produce better outcomes
AMERICAN OSTEOPATHIC ASSOCIATION
A pilot study of 23 adults with newly diagnosed type 2 diabetes found early insulin therapy to be as effective as 15 months of oral therapy and may improve the body's ability to produce insulin.
MEETINGOMED 2015
Public Release: 16-Oct-2015
Discovery opens door to new strategy for cancer immunotherapy
DANA-FARBER CANCER INSTITUTE
New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.
JOURNALScienceFUNDERLeRoy Schecter Research Foundation, National Institutes of Health, Arthritis National Research Foundation

2015-10-19 17:26

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• 浙江大学医学院张进课题组－美国梅奥医学中心Hu Li课题组联合招聘博士后

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freelane

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每日生物医药科技动态汇编2015年10月20日

Public Release: 21-Oct-2015
Gene therapy could aid weight loss without affecting bone loss, new research finds
OREGON STATE UNIVERSITY
Delivering the hormone leptin directly to the brain through gene therapy aids weight loss without the significant side effect of bone loss, according to new collaborative research from Oregon State University and University of Florida.
JOURNALJournal of EndocrinologyFUNDERNational Institutes of Health, Department of Defense
Public Release: 21-Oct-2015
Number of postdocs declines for first time, new study shows
FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY
After more than 30 years of steady growth, the number of postdocs in the biological and biomedical sciences is on the decline in the United States, according to a new paper in The FASEB Journal. The study shows that despite continuing increases in the number of PhD students, there was a 5.5 percent loss in the postdoctoral population from 2010-13, the most recent survey year. The findings have important implications for the biomedical workforce.
JOURNALFASEB Journal
Public Release: 21-Oct-2015
Prevalence of marijuana use disorders rises as marijuana use more than doubles in the US
COLUMBIA UNIVERSITY'S MAILMAN SCHOOL OF PUBLIC HEALTH
Marijuana use in the United States more than doubled over the period from 2001-2002 to 2012-2013, while the increase in disorders associated with marijuana use was almost as large for that period. Researchers at the Mailman School of Public Health and Columbia University Medical Center, and colleagues found that nearly three out of 10 marijuana users experienced a marijuana use disorder of abuse or dependence in 2012-13, affecting some 6,846,000 Americans.
JOURNALJAMA PsychiatryFUNDERNIH/National Institute on Drug Abuse
Public Release: 21-Oct-2015
The test tube foals that could help ensure rare breed survival
UNIVERSITY OF LIVERPOOL
The recent birth of two test tube foals in the UK, as part of a collaborative project conducted by leading fertility experts, could help benefit rare breed conservation and horses with fertility problems. The births mark the successful completion of a three-year programme, led by the University of Liverpool, the University of Surrey and Twemlows Stud Farm. The aim of the project was to establish and offer advanced breeding methods that are not routinely available in the UK.

Public Release: 21-Oct-2015
Children who take antibiotics gain weight faster than kids who don't
JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH
Kids who receive antibiotics throughout the course of their childhoods gain weight significantly faster than those who do not, according to new Johns Hopkins Bloomberg School of Public Health research.
JOURNALInternational Journal of ObesityFUNDERNIH/ Eunice Kennedy Shriver National Institute of Child Health & Human Development, Global Obesity Prevention Center at the Johns Hopkins Bloomberg School of Public Health
Public Release: 21-Oct-2015
Blood pressure medication can't undo all damage
NORTHWESTERN UNIVERSITY
Patients on antihypertensive medications are still at greater risk of cardiovascular disease, despite controlled numbers.
JOURNALJAHA: Journal of the American Heart AssociationFUNDERNIH/National Heart, Lung, and Blood Institute, NIH/National Institute on Aging, National Center for Research Resources
Public Release: 21-Oct-2015
Worldwide shift in heart medication delivery required: Study
MCMASTER UNIVERSITY
Many people in the world who need essential heart medicine do not get it, even in rich countries, says new research published today in the medical journal The Lancet. A radical change is required in how such medicines are provided and preventative care organized in health care systems, the authors say.
JOURNALThe LancetFUNDERPopulation Health Research Institute, Canadian Institutes of Health Research, Heart and Stroke Foundation of Ontario, AstraZeneca (Canada), Sanofi-Aventis (France and Canada), Boehringer Ingelheim (Germany and Canada), Servier, GlaxoSmithKline, and others
Public Release: 21-Oct-2015
Diamonds -- a tooth's best friend?
AMERICAN CHEMICAL SOCIETY
Gold, silver and porcelain are among the many materials dentists can use to fix damaged teeth. Soon diamonds -- at least tiny, microscopic ones -- could be added to that list. Scientists have developed a new material with nanodiamonds that has the potential to improve current root canal therapies and help prevent future infection. Their report appears in the journal ACS Nano.
JOURNALACS Nano
Public Release: 21-Oct-2015
New technique permits cell-specific examination of proteins in Alzheimer's brain tissue
NYU LANGONE MEDICAL CENTER / NEW YORK UNIVERSITY SCHOOL OF MEDICINE
NYU Langone Medical Center has developed a novel method to examine the structure and function of proteins at the cell level -- providing greater means to study protein changes found in Alzheimer's disease.
JOURNALScientific Reports

Public Release: 21-Oct-2015
Gardening therapy helps women on long-term sick leave return to work
UNIVERSITY OF GOTHENBURG
Being and working in a garden combined with active job coaching can effectively help women on long-term sick leave return to work. A study conducted at University of Gothenburg explored the reasons for the trend.
JOURNALScandinavian Journal of Caring SciencesMEETING2015 AGU Fall Meeting

2015-10-20 20:10

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freelane 编辑于 2015-10-22 00:55

• 今日一位院长被刺12刀死亡，起因据悉只是200元欠费!

super19830102

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22楼

新的指南建议推迟对具有普通乳腺癌风险女性做第一次乳房造影筛检的时间

新的指南建议推迟对具有普通乳腺癌风险女性做第一次乳房造影筛检的时间
据10月20日发表在《美国医学会杂志》上的一篇文章披露，美国癌症协会更新的乳腺癌筛检指南中的变动为：那些具有普通罹患乳腺癌风险的妇女应该在45岁开始接受常规性的年度乳房造影筛检，但女性仍有机会选择开始年度筛检的时间为早至40岁；55岁或以上的妇女应该过渡至每隔一年（相对于每年）做一次筛检，但她们仍有继续每年做一次筛检的机会；不再建议做常规筛检性的临床乳房检查。
乳腺癌是全世界妇女中的最常见癌症。在美国，估计大约有23万女性会在2015年被诊断罹患乳腺癌。在美国妇女的癌症死因中，乳腺癌继续排在第二位，第一位是肺癌。尽管自1990年以来乳腺癌死亡病例在稳定下降（这主要是因为早期发现和治疗方法得到改善），但在2015年，美国估计有4万又300名女性仍然会死于乳腺癌。根据文章的背景资料，早期发现乳腺癌与乳腺癌疾病和死亡率下降相关。
自从上次在2003年发布美国癌症协会（ACS）对普通风险女性进行乳腺癌筛检更新以来，对随机对照试验的长期随访及对有组织的、基于人群的筛检计划所做的观测研究已经积累了新的证据。这些建议的制定是基于证据的品质及对利弊平衡的判断（纳入了价值和偏好）。
2015年版普通风险女性的乳腺癌筛检建议：
•  从45岁开始，女性应该接受常规性的乳房造影筛检。
•  45岁至54岁女性应该每年进行筛检。
•  年龄55岁及以上女性应该过渡至每2年进行一次筛检，或继续给她们每年都接受一次筛检的机会。
•  40岁至44岁的女性应给予开始每年接受一次筛检的机会。
•  只要妇女的总体健康良好且她们的预期寿命有10年或以上，她们就应该继续接受乳房造影筛检。
•  不再建议对任何年龄的普通风险妇女做临床乳房检查。
作者们写道：“ACS赞同在45岁时开始每年做乳房造影筛检，并在55岁时过渡至每2年做一次乳房造影筛检，与此同时，仍然保留让她们继续每年做一次筛检的选项，因为某些女性可能会根据个人偏好、临床指导或两者兼有而选择这样做。在对40-54岁女性的疾病负担进行仔细检查之后，该指南制定小组（GDG）得出结论：40-44岁女性的疾病负担较小但并非无关紧要，而较高的不良转归累积风险已经不再有必要直接给予在40岁开始接受筛检的建议。”
关于不再建议做定期临床乳房检查（CBE）时，研究人员写道，“由于没有清晰的证据显示CBE显著促成了在40岁前后乳腺癌的检测，这使得GDG得出结论，不再建议对任何年龄的普通风险女性做CBE。”
“这一指南的目的是给公众和临床医生提供指导，它特别适用于医患在临床接触时使用。应该鼓励妇女了解并与她们的医生讨论其家族史和病史，而临床医生应该定期地确定某女性的风险因子概况是否已经改变。如果该妇女具有普通的罹患乳腺癌风险，ACS鼓励在她40岁上下时讨论筛检事宜。ACS还建议为女性提供风险因子、降低风险的信息以及与乳房造影筛检相关的好处、局限性及害处的信息。”
“总之，ACS制定的建议是为了最大程度地减少乳腺癌死亡及减少寿命丧失年数，并同时将美国妇女人群中的相关害处降至最低。ACS承认在某些情况下，利弊平衡将很接近，而女性的价值和偏好范围将会导致不同的决定。这一新的指南旨在给女性就何时开始及何时停止乳房造影筛检以及进行乳腺癌筛检的频度提供指导和灵活性。”
###(doi:10.1001/jama.2015.12783)
社论：美国妇女乳腺癌筛检的新指南
波士顿哈佛医学院的 Nancy L. Keating，M.D.，M.P.H. 和波士顿布莱根妇女医院的Lydia E. Pace，M.D.，M.P.H. 在一篇伴随的社论中写道：“ACS的新指南会让临床医生和女性更容易做出有关乳房造影筛检的决定吗？在某些方面，来自ACS和美国预防服务工作组（USPSTF）所给出的信息（这是2个主要的指南）现在更为一致了。这两个指南同意，对不到45岁的有着普通罹患乳腺癌风险的妇女而言，乳腺X线筛查的害处可能大于裨益。”
“对55岁以上的女性而言，每两年做一次乳房造影可能会提供最佳的利弊平衡。新的ACS建议——对预期寿命不到10年的老年妇女停止做筛检是可行的，它与对功能 vs 实足年龄的日益强调也是一致的。更具挑战性的决定是对那些45-54岁的妇女，对这一年龄组妇女，ACS建议每年进行筛检，但USPSTF则建议对她们不做常规筛检（45-49岁）或每两年做一次筛检（50-54岁）。在与病人沟通时，临床医生必须要将ACS的建议做较频繁的筛检与较年轻妇女所得到的乳房造影筛检的绝对益处较低这一事实进行平衡。” (doi:10.1001/jama.2015.13086)
《美国科学院学报》（PNAS）其他重要新闻发布摘要

父亲压力向后代的传递
科研人员报告说，向小鼠受精卵注射9种微RNA——与没有压力的小鼠相比，有压力的雄性小鼠的精子中的这9种微RNA水平升高——发育成的成体后代与对照组受精卵发育出的小鼠相比，下丘脑基因表达水平改变，对急性压力做出反应的皮质酮的制造减少，这提示了父亲暴露在压力中如何可能影响后代的发育与行为。
论文 #15-08347: “Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress,” 作者Ali B. Rodgers, Christopher P. Morgan, N. Adrian Leu和Tracy L. Bale.
媒体联系人：Tracy L. Bale，美国宾夕法尼亚大学兽医学院 University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA; 电话：215-898-1369; 电子邮件：tbale@vet.upenn.edu
北极结核的基因组学
对来自目前流行结核病的加拿大北部的结核分枝杆菌的遗传分析发现，结核分枝杆菌很可能是在20世纪早期引入此地的，而有利的社会环境而非对一种充分适应环境的菌株的选择，可能帮助了这种疾病的传播。
论文 #15-07071: “Population genomics of Mycobacterium tuberculosis in the Inuit,” 作者Robyn S. Lee 等人
媒体联系人：Marcel A. Behr，加拿大McGill大学卫生中心研究所，McGill国际结核病中心 McGill International TB Centre, The Research Institute of the McGill University Health Centre, Montreal, CANADA; 电话：514-934-1934 x42815; 电子邮件：marcel.behr@mcgill.ca

2015-10-21 06:27

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• 执业医师成绩快出来了，大家快看

super19830102

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23楼

1/研究发现AKI是中风患者高死亡率的一个预测指标
Public Release: 20-Oct-2015
Researchers find AKI a predictor of higher mortality rates for stroke patients
UNIVERSITY OF CINCINNATI ACADEMIC HEALTH CENTER
A University of Cincinnati researcher, in collaboration with other investigators, has found that ischemic and hemorrhagic stroke patients who suffer from acute kidney injury requiring dialysis have higher death rates and greater odds of entering long-term care or nursing facilities after hospitalization.
JOURNAL
Stroke: Journal of the American Heart Association
2 左心室的信室辅助器可以帮助治疗心脏衰竭
Public Release: 20-Oct-2015
Two lefts make it right: Cardiac experts find novel approach to treat heart failure
UNIVERSITY OF CALIFORNIA - SAN DIEGO
A teenage girl faced with sudden rapid heart deterioration, a man in the prime years of his life suffering from debilitating heart failure and a former NFL athlete crippled by end-stage heart failure were all successfully treated with a surgical approach pioneered by cardiac experts at University of California, San Diego School of Medicine.
JOURNAL
Annals of Thoracic Surgery
3 大数据帮助识别癌症驱动基因
Public Release: 20-Oct-2015
'Big Data' used to identify new cancer driver genes
SANFORD-BURNHAM PREBYS MEDICAL DISCOVER INSTITUTE
SBP researchers combine publicly available cancer databases to identify new genes associated with cancer.
JOURNAL
PLOS Computational Biology
FUNDER
Sanford Burnham Prebys Medical Discovery Institute
4 Brainreader可以快速准确测量脑体积，已被FDA批准
Research study validates neuroreader for accurate and fast measurement of brain volumes
Study, published in Journal of Alzheimer's Disease, highlights software's role in tracking key 'vital sign' for brain health
5、NIH的研究揭示了抗疟耐药性在非洲蔓延的风险
NIH study reveals risk of drug-resistant malaria spreading to Africa
NIH/NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Drug-resistant forms of Plasmodium falciparum, the deadliest species among malaria parasites, are able to infect the type of mosquito that is the main transmitter of malaria in Africa, according to findings from scientists at NIAID. The discovery suggests Africa -- where malaria will cause an estimated 400,000 deaths in 2015 -- is more at risk for drug-resistant malaria infections than previously thought, which could further compromise efforts to prevent and eliminate the disease.
JOURNAL
Nature Communications
FUNDER
NIH/National Institute of Allergy and Infectious Diseases

2015-10-21 06:54

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• 公立医院动态编制来了！打破铁饭碗，干不好走人

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freelane

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2015-10-22 00:53

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• 浙大新规：「10万+」也能被认定为学术论文！！？

super19830102

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25楼

1 Gene therapy could aid weight loss without affecting bone loss, new research finds
研究发现基因疗法可以无骨损伤减肥。
2Number of postdocs declines for first time, new study shows
生物学的博士后人数首次出现下降，在30年增长之后。
3 Prevalence of marijuana use disorders rises as marijuana use more than doubles in the US
做柳下惠很难，大麻乱用在美国呈上升趋势
4 The test tube foals that could help ensure rare breed survival
试管小马驹出生，其技术可以帮助保存稀有品种 5Children who take antibiotics gain weight faster than kids who don't
儿童服用抗生素容易变胖 6 Blood pressure medication can't undo all damage
降压药物治疗并不能抵御所有相关风险 7 Worldwide shift in heart medication delivery required: Study
不同国家的心脏病用药需求正在发生改变 8 Diamonds -- a tooth's best friend?
纳米钻石可以改变牙齿根管疗法的缺点 9 New technique permits cell-specific examination of proteins in Alzheimer's brain tissue新技术（laser-capture microdissection-激光捕获显微切割技术）可以帮助对阿尔默茨海默病的脑病变组织蛋白进行细胞特异性检查

2015-10-22 06:08

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• 多位医生被认为「不合理」用药？处罚金额上万！

super19830102

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+1 积分
26楼

1 Gene therapy could aid weight loss without affecting bone loss, new research finds
研究发现基因疗法可以无骨损伤减肥。

2Number of postdocs declines for first time, new study shows
生物学的博士后人数首次出现下降，在30年增长之后。

3 Prevalence of marijuana use disorders rises as marijuana use more than doubles in the US
做柳下惠很难，大麻乱用在美国呈上升趋势

4 The test tube foals that could help ensure rare breed survival
试管小马驹出生，其技术可以帮助保存稀有品种
5Children who take antibiotics gain weight faster than kids who don't
儿童服用抗生素容易变胖
6 Blood pressure medication can't undo all damage
降压药物治疗并不能抵御所有相关风险
7 Worldwide shift in heart medication delivery required: Study
不同国家的心脏病用药需求正在发生改变
8 Diamonds -- a tooth's best friend?
纳米钻石可以改变牙齿根管疗法的缺点
9 New technique permits cell-specific examination of proteins in Alzheimer's brain tissue新技术（laser-capture microdissection-激光捕获显微切割技术）可以帮助对阿尔默茨海默病的脑病变组织蛋白进行细胞特异性检查

2015-10-22 06:09

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• 关于颈动脉粥样硬化和狭窄治疗的最新指南

super19830102

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28楼

How parasites take a bigger bite
MCGILL UNIVERSITY HEALTH CENTRE
A team of international scientists led by the Research Institute of the McGill University Health Centre uncovered an important mechanism behind Leishmania, a deadly parasitic disease transmitted by sandflies. In a new study published today in Cell Reports, researchers described how key molecules known as exosomes, boost the process by which the Leishmania parasite infects humans and other mammals. These findings could lead to the development of new potential vaccine targets and diagnostic tools.
JOURNALCell ReportsFUNDERCanadian Institutes of Health Research

Public Release: 22-Oct-2015
Researchers identify potential new leukemia drug target
ROCKEFELLER UNIVERSITY
In some cases of acute myeloid leukemia, a mutant protein is known to cause dramatic changes in gene expression. Now researchers have identified a second protein with similar function that plays an even broader role in the disease.
JOURNALGenes and Development
Public Release: 22-Oct-2015
Monitoring critical blood levels in real time in the ICU
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE
For patients in intensive care, knowing how much glucose, lactate and other substances are in the blood is a question of life or death. EPFL has developed a miniaturized microfluidic device that will allow medical staff to monitor these levels in real time and react more quickly. It was unveiled on Oct. 22nd, 2015 in Atlanta.
MEETINGIEEE BioCAS 2015FUNDERNano-tera.ch

Public Release: 22-Oct-2015
New hope for the treatment of multiple sclerosis
MCGILL UNIVERSITY HEALTH CENTRE
A new study led by researchers at the Montreal Neurological Institute and Hospital of McGill University and the MUHC, gets closer to identifying the mechanisms responsible for multiple sclerosis and makes headway in the search for better treatments.
JOURNALScience Translational MedicineFUNDERResearch Foundation of the Multiple Sclerosis Society of Canada
Public Release: 22-Oct-2015
Allina Health study could save breast cancer patients time, money and side effects
ALLINA HEALTH
The study was designed to determine the tumor and patient characteristics which predicted lower risk of breast cancer recurrence in women with invasive lobular carcinoma. Classic ILC is more likely to respond to edocrine treatment than chemotherapy.
JOURNALClinical Breast CancerFUNDEREngelsma Family Foundation
Public Release: 22-Oct-2015
New curriculum teaches patient-centric practices for 21st-century docs
PENN STATE
Medical students at Penn State are now receiving training in health systems sciences and patient navigation, along with the traditional areas of medical education.
JOURNALAcademic MedicineFUNDERAmerican Medical Association
Public Release: 22-Oct-2015
Gene therapy treats all muscles in the body in muscular dystrophy dogs
UNIVERSITY OF MISSOURI-COLUMBIA
Muscular dystrophy, which affects approximately 250,000 people in the US, occurs when damaged muscle tissue is replaced with fibrous, fatty or bony tissue and loses function. For years, scientists have searched for a way to successfully treat the most common form of the disease, Duchenne Muscular Dystrophy (DMD), which primarily affects boys. Now, a team of University of Missouri researchers have successfully treated dogs with DMD and say that human clinical trials are being planned in the next few years.
JOURNALHuman Molecular GeneticsFUNDERUS Department of Defense, National Institutes of Health
Public Release: 22-Oct-2015
NIH-funded study reveals why malaria vaccine only partially protected children, infants
NIH/NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Using new, highly sensitive genomic sequencing technology, an international team of researchers has found new biological evidence to help explain why the malaria vaccine candidate RTS,S/AS01 (called RTS,S) provided only moderate protection among vaccinated children during clinical testing. The researchers, funded in part by the National Institute of Allergy and Infectious Diseases at the National Institutes of Health, found that genetic variability in the surface protein targeted by the RTS,S vaccine likely played a significant role.
JOURNALNew England Journal of MedicineFUNDERNIH/National Institute of Allergy and Infectious Diseases
Public Release: 22-Oct-2015
CWRU biologists find keys to driving a cockroach
CASE WESTERN RESERVE UNIVERSITY
Researchers at Case Western Reserve University have identified neurons in a cockroach's brain that control whether the insect walks slow or fast, turns right or left or downshifts to climb. Electrical stimulation selectively applied to these central-complex cells alters reflexes and consistently causes the insects to replicate movements.
JOURNALCurrent BiologyFUNDERNational Science Foundation, Air Force Office of Scientific Research

2015-10-23 05:54

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super19830102 编辑于 2015-10-23 06:06

• 住培医生拒绝加班被处理，引医生热议！

super19830102

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29楼

1 How parasites take a bigger bite
分子机制解释利什曼原虫的感染人类和其他哺乳动物的过程，或有助于新苗研发。
利什曼原虫病是由利什曼属的各种原虫所致人兽共患的一种以慢性经过为主的寄生虫疾病。影响全球超过1200万人，每年有并有超过130万新发病例。

2Researchers identify potential new leukemia drug target
研究发现治疗白血病的新靶标
从白血病的突变蛋白着手，研究其关键酶JMJD1C，并最终寻找到了负责编辑该酶的两个关键蛋白。
3Monitoring critical blood levels in real time in the ICU
如何在ICU病房实施检测血液
由3D打印技术制备，安装生物传感器，可以检测血液或者血清中关键物质的水平。已经成功地在老鼠试验，体积小巧，已经有很多厂商对该产品感兴趣。设备首次亮相于10月22日在亚特兰大在2015年BioCAS会议。
4New hope for the treatment of multiple sclerosis
治疗多发性硬化症的新希望
多发性硬化（MS）是一种T细胞的疾病，但研究发现另一种类型的白血细胞B细胞对该病也有很大影响，B细胞耗竭疗法（BCDT）在在临床上对该疾病治疗有显著疗效。文章阐明了B细胞影响该疾病的分子机制以及BCDT的作用机理。
5 Allina Health study could save breast cancer patients time, money and side effects
Allina Health研究可以帮助乳腺癌患者节省时间，金钱并减少副作用。
大多数患有浸润性小叶乳腺癌的患者，可以单独使用激素疗法，而不需要与化疗合用，通过利用OncotypeDX®基因表达检测，并通过孕激素受体表达，Ki-67（增殖指数），雌激素受体表达，患者年龄和肿瘤大小，研究确立了一个模型。Oncotype DX测试费用约$ 4,000，由Genomic Health公司生产。
6 New curriculum teaches patient-centric practices for 21st-century docs
7 Gene therapy treats all muscles in the body in muscular dystrophy dogs NIH-funded study reveals why malaria vaccine only partially protected children, infants CWRU biologists find keys to driving a cockroach

2015-10-23 06:31

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super19830102 编辑于 2015-10-23 06:49

• 今日一位院长被刺12刀死亡，起因据悉只是200元欠费!

楼主

freelane

铁杆站友

30楼

每日生物医药科技动态汇编2015年10月23日

Public Release: 23-Oct-2015
A new algorithm to predict the dynamic language of proteins
CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO)
Researchers have developed the first computational method based on evolutionary principles to predict the changes in shape that proteins experience to carry out their functions. This method is a step forward in the study of protein dynamics, of great importance for the design of drugs and the investigation of genetic diseases such as cancer. The work, published in the journal 'Proceedings of the National Academy of Sciences,' was prepared by researchers at the CNIO and University College London.
JOURNALProceedings of the National Academy of Sciences
Public Release: 23-Oct-2015
Focus on treatment decisions: Doctor and patient should decide together
DEUTSCHES AERZTEBLATT INTERNATIONAL
This edition of Deutsches Ärzteblatt International, which focuses on patient involvement, contains two original articles investigating the following questions: Do patients benefit from shared decision making? Is treatment more effective as a result? How do physicians gain from training in shared decision making? http://www.aerzteblatt.de/int/archive/past?heftid=5912
JOURNALDeutsches Ärzteblatt International
Public Release: 23-Oct-2015
Depression too often reduced to a checklist of symptoms
KU LEUVEN
How can you tell if someone is depressed? The Diagnostic and Statistical Manual of Mental Disorders (DSM) -- the 'bible' of psychiatry -- diagnoses depression when patients tick off a certain number of symptoms on the DSM checklist. A large-scale quantitative study coordinated at KU Leuven, Belgium, now shows that some symptoms play a much bigger role than others in driving depression, and that the symptoms listed in DSM may not be the most useful ones.
JOURNALJournal of Affective Disorders
Public Release: 23-Oct-2015
Signs of faster ageing process identified through gene research
UNIVERSITY OF EXETER
New research has shed light on the molecular changes that occur in our bodies as we age.
JOURNALNature Communications
Public Release: 23-Oct-2015
Online gambling to get safer through better prediction of addiction
ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL
A new 'early warning' system that automatically informs gamblers as soon as their behaviour shows signs of turning into an addiction is helping people engage in the pastime responsibly. The system pinpoints whether a player's gambling patterns are exhibiting signs of risk and starting to match those of previous players who asked online gambling sites to block them, for a fixed period, to stop them becoming 'hooked' -- an option known as 'self-exclusion'.

Public Release: 23-Oct-2015
New DNA research reveals undiscovered white dots on the map
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES
Researchers at the University of Copenhagen have located a previously unknown function in the so-called histones, which allows for an improved understanding of how cells protect and repair DNA damages. This knowledge may eventually result in better treatments for diseases such as cancer.
JOURNALNature
Public Release: 23-Oct-2015
Sarcoidosis: Surface marker allows new diagnostic approaches
HELMHOLTZ ZENTRUM MÜNCHEN - GERMAN RESEARCH CENTER FOR ENVIRONMENTAL HEALTH
A team of scientists at the Helmholtz Zentrum München together with colleagues of the Ludwig Maximilians University Munich recently developed a new strategy to determine monocyte subsets involved in diseases. The results published in the journal 'Blood' could help facilitating the diagnosis of sarcoidosis and may improve the respective patient management.
JOURNALBlood
Public Release: 23-Oct-2015
Alzheimer risk impairs 'satnav' function of the brain
RUHR-UNIVERSITY BOCHUM
Young adults with genetically increased Alzheimer's risk have altered activation patterns in a brain region that is crucial for spatial navigation. This is reported by the team headed by Prof. Nikolai Axmacher from the Ruhr-Universität Bochum, together with colleagues from the universities of Bonn, Nijmegen and Ulm in the journal Science, which appears on Oct. 23.
JOURNALScience

Public Release: 23-Oct-2015
Active body, active mind: The secret to a younger brain may lie in exercising your body
UNIVERSITY OF TSUKUBA
It is widely recognized that our physical fitness is reflected in our mental fitness, especially as we get older. How does being physically fit affect our aging brains? Neuroimaging studies, in which the activity of different parts of the brain can be visualized, have provided some clues. Until now, however, no study has directly linked brain activation with both mental and physical performance.
JOURNALNeuroImage

Public Release: 23-Oct-2015
Mini-kidney organoids re-create disease in lab dishes
UNIVERSITY OF WASHINGTON HEALTH SCIENCES/UW MEDICINE
Using kidney organoids grown from stem cells and gene editing, scientists have re-created human kidney disease in lab petri dishes. The findings pave the way for personalized kidney drug discovery.
JOURNALNature CommunicationsFUNDERNational Institutes of Health, NCATS Loan Repayment Program, National Kidney Foundation, Harvard Stem Cell Institute, Institute for Stem Cell and Regenerative Medicine, Kidney Research Institute,

2015-10-24 01:34

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31楼

每日生物医药科技动态汇编2015年10月23日
A new algorithm to predict the dynamic language of proteins
新模型来预测蛋白质动态结构，对于药物设计以及遗传疾病的研究都有重要意义
Focus on treatment decisions: Doctor and patient should decide together
医生和患者之间共同探讨，决定治疗方案。
Depression too often reduced to a checklist of symptoms
如何判断患有抑郁症，之前基本都是靠精神障碍的诊断和统计手册（DSM）来进行诊断，但研究发现一些在DSM不重要的因素可能起到关键作用
Signs of faster ageing process identified through gene research
通过基因研究确定了加速衰老的迹象
Online gambling to get safer through better prediction of addiction New DNA research reveals undiscovered white dots on the map Sarcoidosis: Surface marker allows new diagnostic approaches Alzheimer risk impairs 'satnav' function of the brain
Active body, active mind: The secret to a younger brain may lie in exercising your body
Mini-kidney organoids re-create disease in lab dishes

2015-10-24 10:04

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每日生物医药科技动态汇编2015年10月24日

Public Release: 23-Oct-2015
Deadly fish virus still present in Wisconsin lake
UNIVERSITY OF WISCONSIN-MADISON
In May 2007, hundreds of freshwater drum -- also known as sheepshead -- turned up dead in Lake Winnebago and nearby Little Lake Butte des Morts, both inland lakes near Oshkosh, Wis. The fish were splotched with red and their eyes were swollen and bulging. The Wisconsin Department of Natural Resources launched a quick response and, working with the Wisconsin Veterinary Diagnostic Laboratory, quickly learned that a deadly virus was responsible: viral hemorrhagic septicemia virus, or VHSv.
JOURNALJournal of Clinical Microbiology

Public Release: 23-Oct-2015
A new algorithm to predict the dynamic language of proteins
CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO)
Researchers have developed the first computational method based on evolutionary principles to predict the changes in shape that proteins experience to carry out their functions. This method is a step forward in the study of protein dynamics, of great importance for the design of drugs and the investigation of genetic diseases such as cancer. The work, published in the journal Proceedings of the National Academy of Sciences, was prepared by researchers at the CNIO and University College London.
JOURNALProceedings of the National Academy of Sciences
Public Release: 23-Oct-2015
Focus on treatment decisions: Doctor and patient should decide together
DEUTSCHES AERZTEBLATT INTERNATIONAL
This edition of Deutsches Ärzteblatt International, which focuses on patient involvement, contains two original articles investigating the following questions: do patients benefit from shared decision making? Is treatment more effective as a result? How do physicians gain from training in shared decision making?
JOURNALDeutsches Ärzteblatt International
Public Release: 23-Oct-2015
Depression too often reduced to a checklist of symptoms
KU LEUVEN
How can you tell if someone is depressed? The Diagnostic and Statistical Manual of Mental Disorders (DSM) -- the 'bible' of psychiatry -- diagnoses depression when patients tick off a certain number of symptoms on the DSM checklist. A large-scale quantitative study coordinated at KU Leuven, Belgium, now shows that some symptoms play a much bigger role than others in driving depression, and that the symptoms listed in DSM may not be the most useful ones.
JOURNALJournal of Affective Disorders
Public Release: 23-Oct-2015
Signs of faster ageing process identified through gene research
UNIVERSITY OF EXETER
New research has shed light on the molecular changes that occur in our bodies as we age.
JOURNALNature Communications
Public Release: 23-Oct-2015
Online gambling to get safer through better prediction of addiction
ENGINEERING AND PHYSICAL SCIENCES RESEARCH COUNCIL
A new 'early warning' system that automatically informs gamblers as soon as their behaviour shows signs of turning into an addiction is helping people engage in the pastime responsibly. The system pinpoints whether a player's gambling patterns are exhibiting signs of risk and starting to match those of previous players who asked online gambling sites to block them, for a fixed period, to stop them becoming 'hooked' -- an option known as 'self-exclusion'.

Public Release: 23-Oct-2015
New DNA research reveals undiscovered white dots on the map
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES
Researchers at the University of Copenhagen have located a previously unknown function in the so-called histones, which allows for an improved understanding of how cells protect and repair DNA damages. This knowledge may eventually result in better treatments for diseases such as cancer.
JOURNALNature
Public Release: 23-Oct-2015
Sarcoidosis: Surface marker allows new diagnostic approaches
HELMHOLTZ ZENTRUM MÜNCHEN - GERMAN RESEARCH CENTER FOR ENVIRONMENTAL HEALTH
A team of scientists at the Helmholtz Zentrum München together with colleagues of the Ludwig Maximilians University Munich recently developed a new strategy to determine monocyte subsets involved in diseases. The results published in the journal 'Blood' could help facilitating the diagnosis of sarcoidosis and may improve the respective patient management.
JOURNALBlood
Public Release: 23-Oct-2015
Alzheimer risk impairs 'satnav' function of the brain
RUHR-UNIVERSITY BOCHUM
Young adults with genetically increased Alzheimer's risk have altered activation patterns in a brain region that is crucial for spatial navigation. This is reported by the team headed by Professor Nikolai Axmacher from the Ruhr-Universität Bochum, together with colleagues from the universities of Bonn, Nijmegen and Ulm in the journal Science, which appears on Oct. 23.
JOURNALScience

2015-10-24 11:07

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34楼

每日生物医药科技动态汇编2015年10月26日

Public Release: 26-Oct-2015
Molecular motor grows cell's microtubules
PENN STATE
Motor proteins that pause at the ends of microtubules and produce pushing forces can also stimulate their growth, according to researchers at Penn State. The proteins' function could be a critical component in understanding cell division and nerve branching and growth.
JOURNALNature CommunicationsFUNDERNIH/National Institute of General Medical Sciences
Public Release: 26-Oct-2015
Reduction in Amazon deforestation avoids 1,700 deaths per year
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO
Because of decreasing deforestation and emissions from forest fires in the Amazon, the amount of particulate matter, ozone, carbon monoxide and other atmospheric pollutants released by burning biomass has fallen by 30 percent on average in dry season in Brazil, Paraguay, Bolivia and Argentina. This improvement in the region's air quality may be helping to prevent the premature deaths of some 1,700 adults per year throughout South America, according studies made in Brazil, UK and USA.
JOURNALNature GeoscienceFUNDERSão Paulo Research Foundation
Public Release: 26-Oct-2015
Scientists uncover signal for when a pregnant woman is about to go into labor
UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTON
Researchers from the University of Texas Medical Branch at Galveston have uncovered a cellular signal in the amniotic fluid around the fetus that builds up when a pregnant woman is about to go into labor. The findings were recently published in PLOS ONE.
JOURNALPLOS ONE
Public Release: 26-Oct-2015
Insulin cells determine weight-loss surgery success rate
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES
Danish researchers have found that the ability to produce insulin is pivotal to the success of weight-loss surgery in patients with type 2 diabetes. The study provides a better point of departure for advise and determining which patients will benefit from surgery.
JOURNALJournal of Physiology
Public Release: 26-Oct-2015
Wives take problems to heart, husbands get frustrated
RUTGERS UNIVERSITY
In a new Rutgers and University of Michigan study, published in the Journal of Gerontology: Social Sciences, the sociologist who found that 'A Happy Wife, Means a Happy Life' looked at sadness, worry and frustration -- among the most common negative emotions reported by older adults -- and discovered that men and women in long-term marriages deal with marriage difficulties differently.
JOURNALJournal of Gerontology: Psychological Sciences and Social Sciences

Public Release: 26-Oct-2015
Researchers solve longtime puzzle about how we learn
JOHNS HOPKINS UNIVERSITY
Neurologically speaking, how did Pavlov's dogs learn to associate a ringing bell with a delayed reward? Scientists have had a working theory, but researchers have now proved it.
JOURNALNeuronFUNDERScience of Learning Institute, National Institutes of Health
Public Release: 26-Oct-2015
Females more promiscuous in colder climates, says insect study
UNIVERSITY OF EXETER
Females have more sexual partners when they live in colder climates and are happier being monogamous when it is hotter, a study into the behavior of insects has found. Researchers at the University of Exeter also found that some female fruit flies are genetically programmed to have a large number of mates and will do so whatever the weather, while others will consistently stick to one mate.
JOURNALBehavioral EcologyFUNDERNatural Environment Research Council

Public Release: 26-Oct-2015
Researchers discover an epilepsy switch
UNIVERSITY OF BONN
Scientists at the University of Bonn and the Hebrew University of Jerusalem have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals. The results are now being published in the journal 'Nature Communications'.
JOURNALNature Communications
Public Release: 26-Oct-2015
DNA test for Down's syndrome on the NHS could save lives
WILEY
Offering pregnant women a DNA test for Down's syndrome on the NHS would reduce the dependency on invasive tests and potentially save the lives of unborn babies, a study shows.
JOURNALUltrasound in Obstetrics and Gynecology
Public Release: 26-Oct-2015
Massive screen of drug combinations may find treatment for resistant, BRAF-mutant melanoma
MASSACHUSETTS GENERAL HOSPITAL
A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination -- pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway -- was discovered through one of the largest screens of cancer drug combinations conducted to date.
JOURNALPLOS ONEFUNDERNational Institutes of Health

2015-10-26 23:35

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• 北京马拉松参赛者心跳骤停，所谓「标准」抢救竟又是 CPR 错用？！！

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35楼

每日生物医药科技动态汇编2015年10月27日

Public Release: 27-Oct-2015
Study finds complete symptom resolution reduces risk of depression recurrence
UNIVERSITY OF CALIFORNIA - SAN DIEGO
People who have had an episode of major depression are at high risk for having another episode. Now, researchers at University of California, San Diego School of Medicine have found that the risk of recurrence is significantly lower for people with complete, rather than partial depressive symptom resolution.
JOURNALJournal of Clinical PsychiatryFUNDERNational Institutes of Health
Public Release: 27-Oct-2015
Grant funds computer simulation to train social work students, clinicians
UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
A federal grant of more than $919,000 from the Substance Abuse and Mental Health Services Administration will fund one new course at the University of Illinois and support training for clinicians at area agencies in conducting early interventions with people who abuse substances.
FUNDERSubstance Abuse Mental Health Services Administration

Public Release: 27-Oct-2015
UT Southwestern researchers identify an enzyme as a major culprit of autoimmune diseases
UT SOUTHWESTERN MEDICAL CENTER
Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report.
JOURNALProceedings of the National Academy of SciencesFUNDERNational Institutes of Health, Welch Foundation, Cancer Prevention and Research Institute of Texas, Lupus Research Institute, Howard Hughes Medical Institute
Public Release: 27-Oct-2015
Genetic tests of amniotic fluid could guide timing of delicate births
CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER
Analyzing gene expression of an expectant mother's amniotic fluid could give doctors an important tool for deciding when it is safe to deliver premature babies. Researchers at Cincinnati Children's Hospital Medical Center report a way to test RNA and specific genetic signatures in amniotic fluid to see whether fetal lungs -- and potentially other organs -- are mature enough for a safe and viable delivery. The paper is published online in the journal BMC Medical Genomics.
JOURNALBMC Medical Genomics
Public Release: 27-Oct-2015
Restoring testosterone rather than replacing it helps safeguard a man's fertility
WILEY
Restoring testosterone production in men may be as effective as replacing it, without compromising their fertility. Two phase III clinical trials show that a drug that restores the body's natural production of testosterone has no negative effect on a man's sperm count while a topical testosterone gel causes a significant drop. The findings, which are published in BJU International, could change the way men are treated for low testosterone.
JOURNALBJU International
Public Release: 27-Oct-2015
Driving with glaucoma? Some patients increase scanning to adapt for impaired vision
WOLTERS KLUWER HEALTH
Some people with glaucoma-related binocular (both eyes) vision loss can pass a standard driving test by adopting increased visual scanning behavior, reports a study in the October issue of Optometry and Vision Science, official journal of the American Academy of Optometry. The journal is published by Wolters Kluwer.
JOURNALOptometry and Vision Science
Public Release: 27-Oct-2015
Potential new therapy for triple-negative breast cancer shows promise in lab studies
VAN ANDEL RESEARCH INSTITUTE
Recent laboratory findings provide novel insight into potential new therapeutic approaches for triple-negative breast cancer, a particularly difficult to treat and aggressive form of the disease.
JOURNALClinical Cancer Research
Public Release: 27-Oct-2015
When it comes to children's ability to think, weight and activity level both matter, study finds
MEDICAL COLLEGE OF GEORGIA AT GEORGIA REGENTS UNIVERSITY
Weight and physical activity levels are both factors in a child's ability to acquire and use knowledge, a new study finds.
JOURNALPediatric Exercise Science

Public Release: 27-Oct-2015
Mental maps: Route-learning changes brain tissue
CARNEGIE MELLON UNIVERSITY
Fifteen years ago, a study showed that the brains of London cab drivers had an enlargement in the hippocampus, a brain area associated with navigation. But questions remained: Did the experience of navigating London's complex system of streets change their brains, or did only the people with larger hippocampi succeed in becoming cab drivers? Now, Carnegie Mellon University scientists have determined that learning detailed navigation information causes the hippocampal brain changes. The findings establish a critical link between structural and functional brain alteration.
JOURNALNeuroImageFUNDEROffice of Naval Research
Public Release: 27-Oct-2015
RI Hospital researcher confirms praziquantel safe after first trimester
LIFESPAN
Rhode Island Hospital researchers confirmed that praziquantel to treat schistosomiasis is safe to give pregnant women after the first trimester. The finding could prove critical to the care of pregnant and lactating women with schistosomiasis who are denied praziquantel. The study was published in The Lancet Infectious Diseases.
JOURNALLancet Infectious DiseasesFUNDERNational Institutes of Health, NIH/National Institute of Allergy and Infectious Diseases

2015-10-28 02:01

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每日生物医药科技动态汇编2015年10月29日

2015-10-30 14:59

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freelane 编辑于 2015-10-30 15:02

• 住培医生拒绝加班被处理，引医生热议！

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每日生物医药科技动态汇编2015年10月30日

Public Release: 30-Oct-2015
Treatment of severe acne hampered by antibiotic overuse and delays in prescribing more potent medication
NYU LANGONE MEDICAL CENTER / NEW YORK UNIVERSITY SCHOOL OF MEDICINE
A medical records analysis by researchers at NYU Langone Medical Center concludes that physicians who treat severe acne leave too many patients on ineffective antibiotics for far too long before prescribing more potent needed therapy with the medication isotretinoin, sometimes known by its former brand name Accutane.
JOURNALJournal of the American Academy of DermatologyFUNDERNYU Langone
Public Release: 30-Oct-2015
Kids meals, toys, and TV advertising: A triple threat to child health
ELSEVIER HEALTH SCIENCES
Fast food companies advertise children's meals on TV with ads that feature toy premiums, and it has been suggested that the use of these toy premiums may prompt children to request eating at fast food restaurants. In a new study scheduled for publication in The Journal of Pediatrics, researchers found that the more children watched television channels that aired ads for children's fast food meals, the more frequently their families visited those fast food restaurants.
JOURNALJournal of Pediatrics
Public Release: 29-Oct-2015
Factor found to balance medically useful stem cell qualities
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE
A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.
JOURNALCell Stem CellFUNDEREllison Medical Foundation Senior Scholar Award in Aging, National Institutes of Health, New York State Department of Health/Empire State Stem Cell Fund
Public Release: 29-Oct-2015
Dartmouth researchers shed light on protein-related diseases
DARTMOUTH COLLEGE
Dartmouth researchers have found that some proteins turn into liquid droplets on the way to becoming toxic solids implicated in neurodegenerative diseases and other genetic disorders.
JOURNALMolecular Cell

Public Release: 29-Oct-2015
New class of DNA repair enzyme discovered
VANDERBILT UNIVERSITY
A new class of DNA repair enzyme has been discovered which demonstrates that a much broader range of damage can be removed from the double helix in ways that biologists did not think were possible.
JOURNALNatureFUNDERNational Science Foudation, National Institutes of Health

Public Release: 29-Oct-2015
Study spells out why some insects kill their mothers
UNIVERSITY OF CALIFORNIA - RIVERSIDE
Among social insects, why does it pay for workers to help the queen in some situations but then also pay to kill her in others? What explains why some queens get killed and not others, and why kill her at all? Kevin Loope, a postdoctoral researcher at the University of California, Riverside, explored these questions, and found that by eliminating the queen, a matricidal worker frees the way for workers to lay male eggs.
JOURNALCurrent BiologyFUNDERNational Science Foundation
Public Release: 29-Oct-2015
Nuclear membrane repairs the 'dark matter' of DNA
UNIVERSITY OF SOUTHERN CALIFORNIA
The nuclear membrane isn't just a protective case around the nucleus -- it actually repairs catastrophically broken DNA strands.
JOURNALNature Cell BiologyFUNDERUSC Gold Family Fellowship, USC Research Enhancement Fellowship, USC Provost Fellowship, Rose Hills Foundation, National Institute of Health
Public Release: 29-Oct-2015
Hair-GEL online tool gives bird's eye view of hair follicle formation
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE
Mount Sinai researchers create a resource to help uncover the molecular controls that generate skin and hair.
JOURNALDevelopmental CellFUNDERNIH/National Institute of Arthritis, Arthritis and Musculoskeletal and Skin Diseases, New York State Department of Health, Irma T. Hirschl Trust

Public Release: 29-Oct-2015
Caught in the act: New wasp species emerging
RICE UNIVERSITY
A new study from biologists at Rice University, the University of Notre Dame, Michigan State University, the University of Iowa and the University of Florida finds that recent evolutionary changes for the fruit fly known as the 'apple maggot' is having a domino effect on three predatory wasp species.
JOURNALProceedings of the National Academy of SciencesFUNDERNational Science Foundation, Indiana Academy of Science, Entomological Society of America, Sigma Xi
Public Release: 29-Oct-2015
Gut bacteria could be blamed for obesity and diabetes
PENN STATE
An excess of bacteria in the gut can change the way the liver processes fat and could lead to the development of metabolic syndrome, according to health researchers.
JOURNALCell MetabolismFUNDERNational Institutes of Health

2015-10-30 15:07

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