发帖
每发1个新帖
可以获得0.5个丁当奖励
回帖

【medical-news】研究者致力于减少未来肝移植的必要

查看全部
页码直达：
直达末页

楼主

逃

神经科

丁香园管理员

1楼

这个帖子发布于14年零2天前，其中的信息可能已发生改变或有所发展。

Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells –possibly dormant from the earliest developmental stage of a human being – which have the potential to mature into different cells types and help repair a failing liver. Their newly-published findings could pave the way for alternative treatments using cell replacements instead of organ transplants for those with liver failure.

A functioning liver is essential for human survival with liver failure ultimately resulting in death, and liver transplantation is presently the only treatment for acute and chronic liver failure. However, the supply of donor livers is insufficient to meet demand, and in the United Kingdom, 20% of patients waiting for a liver transplant will die from liver failure before a suitable donated organ becomes available.

Head of the group Dr James Ross said: "Potentially, cell replacement therapies could provide alternative treatments that would avoid difficulties associated with obtaining sufficient donor organ transplantation. We have now identified primitive cells with the potential to mature into different cell types within and out with the liver. It is possible that these cells lie dormant in the adult liver and may be the source of repair cells that are activated by severe liver injury."

"The liver is often able to repair and heal itself following injury or damage and this occurs in one of three ways. Firstly, mature liver cells have a well recognised and extensive capacity to divide in response to injury. Secondly, in response to massive loss of functioning liver tissue, a population of primitive liver stem cells may be stimulated to proliferate and develop into mature liver cells. The third mechanism of liver repair involves circulating stem cells originating from other sources, such as the bone marrow, and it is possible that these cells may be recruited into the liver and form new liver cells."

邀请讨论

搜索

2006-07-10 03:02 浏览 : 1034 回复 : 12

投票
收藏
打赏
引用
分享
- 微信扫一扫
- 新浪微博
- 丁香客
- 复制网址
举报
- 广告宣传推广
- 政治敏感、违法虚假信息
- 恶意灌水、重复发帖
- 违规侵权、站友争执
- 附件异常、链接失效
- 其他

• 中山三院上线统计（更新）

楼主

逃

神经科

丁香园管理员

4楼

shuelly
It is possible that these cells lie dormant in the adult liver and may be the source of repair cells that are activated by severe liver injury."这种细胞很有可能在成人肝脏中处于休眠状态并是在严重肝脏损伤时修复细胞激活的来源。
我觉得最后几个字读来有些便扭，不如这样：有可能这些细胞在成人肝脏中处于休眠状态，并在严重肝损伤发生时成为被激活的修复细胞的来源。

The liver is often able to repair and heal itself following injury or damage and this occurs in one of three ways.肝脏通常能在损伤或损害后通过三种方式中的一种进行修复和治疗。
译文中没有体现原文中：itself的意思。我以为在译文中加入“自我修复”更好：肝脏通常能在损伤或损害后通过通过三种方式中的一种进行自我修复和治疗。

不知以为如何？

比原来的翻译要好！

2006-07-12 02:04

投票
收藏
打赏
引用
分享
- 微信扫一扫
- 新浪微博
- 丁香客
- 复制网址
举报
- 广告宣传推广
- 政治敏感、违法虚假信息
- 恶意灌水、重复发帖
- 违规侵权、站友争执
- 附件异常、链接失效
- 其他

• AVF血栓介入治疗中肘部穿静脉栓塞的处理

楼主

逃

神经科

丁香园管理员

10楼

carolxu 站友:您好！

自选翻译请另开新贴

另外，您的文字组织欠流畅，我们很难阅读理解，请注意meiranzhi 站友的点评！

2006-07-13 01:15

投票
收藏
打赏
引用
分享
- 微信扫一扫
- 新浪微博
- 丁香客
- 复制网址
举报
- 广告宣传推广
- 政治敏感、违法虚假信息
- 恶意灌水、重复发帖
- 违规侵权、站友争执
- 附件异常、链接失效
- 其他

• 中山三院上线统计（更新）

科技动态

【medical-news】研究者致力于减少未来肝移植的必要

提示

丁香园旗下网站

关于丁香园

官方链接

科技动态

分享到：

微信扫一扫

【medical-news】研究者致力于减少未来肝移植的必要

微信扫一扫

微信扫一扫

微信扫一扫

提示

丁香园旗下网站

关于丁香园

官方链接